The incidence, predictors and outcomes of QTc prolongation in critically ill patients

To study the incidence, predictors and outcomes of QTc prolongation (≥500 ms) during ICU admission. Prospective observational study of patients admitted to a tertiary ICU during a two-month period. We obtained daily data on QTc intervals and arrhythmias from ICU monitors. We performed univariate and...

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Bibliographic Details
Published in:Journal of critical care 2019-12, Vol.54, p.244-249
Main Authors: Russell, Hollie, Churilov, Leonid, Toh, Lisa, Eastwood, Glenn M., Bellomo, Rinaldo
Format: Article
Language:English
Subjects:
Cardiac arrhythmia
Critical care
Critically ill
Data collection
Electrocardiography
Electrolytes
Heart rate
Hospitals
ICU
Illnesses
Mortality
Patients
Potassium
QTc
Sinuses
Statistical analysis
Torsades de Pointes
Ventricular arrhythmia
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Summary:To study the incidence, predictors and outcomes of QTc prolongation (≥500 ms) during ICU admission. Prospective observational study of patients admitted to a tertiary ICU during a two-month period. We obtained daily data on QTc intervals and arrhythmias from ICU monitors. We performed univariate and multivariable analyses to compare patients who did or did not experience QTc prolongation. Of the 257 patients, 93 (36.2%) developed ≥1 episode of QTc ≥500 ms. Such patients had higher APACHE II scores (p 
ISSN:0883-9441
1557-8615
DOI:10.1016/j.jcrc.2019.09.014