Left Ventricular Assist Device as Destination Therapy: a State of the Science and Art of Long-Term Mechanical Circulatory Support

Purpose of Review The purpose of this review is to synthesize and summarize recent developments in the care of patients with end-stage heart failure being managed with a left ventricular assist device (LVAD) as destination therapy. Recent Findings Although the survival of patients treated with LVAD...

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Bibliographic Details
Published in:Current heart failure reports 2019-10, Vol.16 (5), p.168-179
Main Authors: Hanff, Thomas C., Birati, Edo Y.
Format: Article
Language:English
Subjects:
Cardiac Surgery
Cardiology
Imaging
Internal Medicine
Medicine
Medicine & Public Health
Radiology
Section Editors
Topical Collection on Updates in Advanced Heart Failure
Updates in Advanced Heart Failure (E. Rame and M. St. John Sutton
Vascular Surgery
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Summary:Purpose of Review The purpose of this review is to synthesize and summarize recent developments in the care of patients with end-stage heart failure being managed with a left ventricular assist device (LVAD) as destination therapy. Recent Findings Although the survival of patients treated with LVAD continues to improve, the rates of LVAD-associated complication, such as right ventricular failure, bleeding complications, and major infection, remain high, and management of these patients remains challenging. Summary The durability and hemocompatibility of LVAD support have greatly increased in recent years as a result of new technologies and novel management strategies. Challenges remain in the comprehensive care of patients with destination therapy LVADs, including management of comorbidities and optimizing patient function and quality of life.
ISSN:1546-9530
1546-9549
DOI:10.1007/s11897-019-00438-x