Potentialities of Postmortem Magnetic Resonance Imaging for Identification of Live Birth and Stillbirth

The potentialities of postmortem MRI for differential diagnosis of stillbirth and death of a live newborn are studied. The results of MRI and pathomorphological studies of autopsy material from 20 stillborns dead at weeks 22-40 of gestation (group 1) and 19 newborns dead at the age of 2 h to 36 days...

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Bibliographic Details
Published in:Bulletin of experimental biology and medicine 2019-10, Vol.167 (6), p.823-826
Main Authors: Tumanova, U. N., Lyapin, V. M., Bychenko, V. G., Shchegolev, A. I., Sukhikh, G. T.
Format: Article
Language:English
Subjects:
Autopsy - methods
Biomedical and Life Sciences
Biomedicine
Cell Biology
Diagnosis, Differential
Female
Fetal Death
Fetal Organ Maturity
Humans
Infant
Infant, Newborn
Infants (Newborn)
Internal Medicine
Laboratory Medicine
Live Birth
Lung - diagnostic imaging
Lung - embryology
Lung - pathology
Magnetic Resonance Imaging
Male
Pathology
Predictive Value of Tests
Pregnancy
Still-birth
Stillbirth
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Summary:The potentialities of postmortem MRI for differential diagnosis of stillbirth and death of a live newborn are studied. The results of MRI and pathomorphological studies of autopsy material from 20 stillborns dead at weeks 22-40 of gestation (group 1) and 19 newborns dead at the age of 2 h to 36 days (group 2) are analyzed. Control group has been formed from 7 live newborns aged 1-7 days. Postmortem MRI provides an objective quantitative evaluation of the intensity of MR signal in various tissues and regions. Calculation of the proportions of MR signal intensities in the lung tissue and environmental air and/or pleural fluid and the respiration values promotes an objective differential diagnosis of stillbirth and death of a live newborn. These data are expected to facilitate clearing out the circumstances and the direct cause of death. However, postmortem MRI cannot completely replace autopsy with complex macroscopic and microscopic studies of organs and tissues.
ISSN:0007-4888
1573-8221
DOI:10.1007/s10517-019-04631-9