Achilles Tendon Rupture Associated with the Use of Fluoroquinolones in Patients Over 60 Years of AGE: Experience From a Single Tertiary Centre

BACKGROUNDFluoroquinolones have been associated with increased risk of tendinopathy and Achilles tendon rupture (ATR), especially in patients over 60 years of age. METHODSA retrospective study was carried out including patients over 60 years of age with ATR attended in our centre over the period 200...

Full description

Saved in:
Bibliographic Details
Published in:Reumatologia clinica 2021, Vol.17 (3), p.141-143
Main Authors: Briones-Figueroa, Andrea, Sifuentes-Giraldo, Walter Alberto, Morell-Hita, José Luis, Vázquez-Díaz, Mónica
Format: Report
Language:eng ; spa
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by
cites
container_end_page 143
container_issue 3
container_start_page 141
container_title Reumatologia clinica
container_volume 17
creator Briones-Figueroa, Andrea
Sifuentes-Giraldo, Walter Alberto
Morell-Hita, José Luis
Vázquez-Díaz, Mónica
description BACKGROUNDFluoroquinolones have been associated with increased risk of tendinopathy and Achilles tendon rupture (ATR), especially in patients over 60 years of age. METHODSA retrospective study was carried out including patients over 60 years of age with ATR attended in our centre over the period 2000-2017. RESULTSWe identified 44 patients with RTA, of whom 18% (8/44) had been previously treated with fluoroquinolones, with a mean age at diagnosis of ATR of 77.37 years and concomitant corticotherapy in 4 of them. In 7patients, the rupture was spontaneous and all required surgical management. A significantly higher frequency of smoking, concomitant corticotherapy and spontaneous ruptures were found in the group treated with fluoroquinolones. CONCLUSIONSATR is an adverse event that can occur in patients over 60 years of age treated with fluoroquinolones, so an adequate risk-benefit assessment should be carried out in this population, especially in the presence of associated risk factors.
doi_str_mv 10.1016/j.reuma.2019.08.004
format report
fullrecord <record><control><sourceid>proquest</sourceid><recordid>TN_cdi_proquest_miscellaneous_2311639282</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2311639282</sourcerecordid><originalsourceid>FETCH-proquest_miscellaneous_23116392823</originalsourceid><addsrcrecordid>eNqVjb1OwzAURi0kJCroE7DckaXBdtr8sEVVAlsRlIGpstJb4sqxg6_Nz0vwzLgSL8C3fMs5OoxdC54JLorbY-YxjiqTXNQZrzLOl2dsJkWZL1blMr9gc6IjT6vkqi7KGftp-kEbgwRbtHtn4SlOIXqEhsj1WgXcw6cOA4QB4YUQ3AE6E51371FbZ5xNqrbwqIJGGwg2H-ih4PCKytOJbu7bO2i_JvQJ6BE670ZQ8Kztm8FU9UEr_w3rZHu8YucHZQjnf3_Jbrp2u35YTKcgUtiNmno0Rll0kXYyF6LIa1nJ_B_oL2LxXyI</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>report</recordtype><pqid>2311639282</pqid></control><display><type>report</type><title>Achilles Tendon Rupture Associated with the Use of Fluoroquinolones in Patients Over 60 Years of AGE: Experience From a Single Tertiary Centre</title><source>Elsevier</source><creator>Briones-Figueroa, Andrea ; Sifuentes-Giraldo, Walter Alberto ; Morell-Hita, José Luis ; Vázquez-Díaz, Mónica</creator><creatorcontrib>Briones-Figueroa, Andrea ; Sifuentes-Giraldo, Walter Alberto ; Morell-Hita, José Luis ; Vázquez-Díaz, Mónica</creatorcontrib><description>BACKGROUNDFluoroquinolones have been associated with increased risk of tendinopathy and Achilles tendon rupture (ATR), especially in patients over 60 years of age. METHODSA retrospective study was carried out including patients over 60 years of age with ATR attended in our centre over the period 2000-2017. RESULTSWe identified 44 patients with RTA, of whom 18% (8/44) had been previously treated with fluoroquinolones, with a mean age at diagnosis of ATR of 77.37 years and concomitant corticotherapy in 4 of them. In 7patients, the rupture was spontaneous and all required surgical management. A significantly higher frequency of smoking, concomitant corticotherapy and spontaneous ruptures were found in the group treated with fluoroquinolones. CONCLUSIONSATR is an adverse event that can occur in patients over 60 years of age treated with fluoroquinolones, so an adequate risk-benefit assessment should be carried out in this population, especially in the presence of associated risk factors.</description><identifier>EISSN: 2173-5743</identifier><identifier>DOI: 10.1016/j.reuma.2019.08.004</identifier><language>eng ; spa</language><ispartof>Reumatologia clinica, 2021, Vol.17 (3), p.141-143</ispartof><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>780,784,4488,27924</link.rule.ids></links><search><creatorcontrib>Briones-Figueroa, Andrea</creatorcontrib><creatorcontrib>Sifuentes-Giraldo, Walter Alberto</creatorcontrib><creatorcontrib>Morell-Hita, José Luis</creatorcontrib><creatorcontrib>Vázquez-Díaz, Mónica</creatorcontrib><title>Achilles Tendon Rupture Associated with the Use of Fluoroquinolones in Patients Over 60 Years of AGE: Experience From a Single Tertiary Centre</title><title>Reumatologia clinica</title><description>BACKGROUNDFluoroquinolones have been associated with increased risk of tendinopathy and Achilles tendon rupture (ATR), especially in patients over 60 years of age. METHODSA retrospective study was carried out including patients over 60 years of age with ATR attended in our centre over the period 2000-2017. RESULTSWe identified 44 patients with RTA, of whom 18% (8/44) had been previously treated with fluoroquinolones, with a mean age at diagnosis of ATR of 77.37 years and concomitant corticotherapy in 4 of them. In 7patients, the rupture was spontaneous and all required surgical management. A significantly higher frequency of smoking, concomitant corticotherapy and spontaneous ruptures were found in the group treated with fluoroquinolones. CONCLUSIONSATR is an adverse event that can occur in patients over 60 years of age treated with fluoroquinolones, so an adequate risk-benefit assessment should be carried out in this population, especially in the presence of associated risk factors.</description><issn>2173-5743</issn><fulltext>true</fulltext><rsrctype>report</rsrctype><creationdate>2021</creationdate><recordtype>report</recordtype><recordid>eNqVjb1OwzAURi0kJCroE7DckaXBdtr8sEVVAlsRlIGpstJb4sqxg6_Nz0vwzLgSL8C3fMs5OoxdC54JLorbY-YxjiqTXNQZrzLOl2dsJkWZL1blMr9gc6IjT6vkqi7KGftp-kEbgwRbtHtn4SlOIXqEhsj1WgXcw6cOA4QB4YUQ3AE6E51371FbZ5xNqrbwqIJGGwg2H-ih4PCKytOJbu7bO2i_JvQJ6BE670ZQ8Kztm8FU9UEr_w3rZHu8YucHZQjnf3_Jbrp2u35YTKcgUtiNmno0Rll0kXYyF6LIa1nJ_B_oL2LxXyI</recordid><startdate>20210301</startdate><enddate>20210301</enddate><creator>Briones-Figueroa, Andrea</creator><creator>Sifuentes-Giraldo, Walter Alberto</creator><creator>Morell-Hita, José Luis</creator><creator>Vázquez-Díaz, Mónica</creator><scope>7X8</scope></search><sort><creationdate>20210301</creationdate><title>Achilles Tendon Rupture Associated with the Use of Fluoroquinolones in Patients Over 60 Years of AGE: Experience From a Single Tertiary Centre</title><author>Briones-Figueroa, Andrea ; Sifuentes-Giraldo, Walter Alberto ; Morell-Hita, José Luis ; Vázquez-Díaz, Mónica</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-proquest_miscellaneous_23116392823</frbrgroupid><rsrctype>reports</rsrctype><prefilter>reports</prefilter><language>eng ; spa</language><creationdate>2021</creationdate><toplevel>online_resources</toplevel><creatorcontrib>Briones-Figueroa, Andrea</creatorcontrib><creatorcontrib>Sifuentes-Giraldo, Walter Alberto</creatorcontrib><creatorcontrib>Morell-Hita, José Luis</creatorcontrib><creatorcontrib>Vázquez-Díaz, Mónica</creatorcontrib><collection>MEDLINE - Academic</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Briones-Figueroa, Andrea</au><au>Sifuentes-Giraldo, Walter Alberto</au><au>Morell-Hita, José Luis</au><au>Vázquez-Díaz, Mónica</au><format>book</format><genre>unknown</genre><ristype>RPRT</ristype><atitle>Achilles Tendon Rupture Associated with the Use of Fluoroquinolones in Patients Over 60 Years of AGE: Experience From a Single Tertiary Centre</atitle><jtitle>Reumatologia clinica</jtitle><date>2021-03-01</date><risdate>2021</risdate><volume>17</volume><issue>3</issue><spage>141</spage><epage>143</epage><pages>141-143</pages><eissn>2173-5743</eissn><abstract>BACKGROUNDFluoroquinolones have been associated with increased risk of tendinopathy and Achilles tendon rupture (ATR), especially in patients over 60 years of age. METHODSA retrospective study was carried out including patients over 60 years of age with ATR attended in our centre over the period 2000-2017. RESULTSWe identified 44 patients with RTA, of whom 18% (8/44) had been previously treated with fluoroquinolones, with a mean age at diagnosis of ATR of 77.37 years and concomitant corticotherapy in 4 of them. In 7patients, the rupture was spontaneous and all required surgical management. A significantly higher frequency of smoking, concomitant corticotherapy and spontaneous ruptures were found in the group treated with fluoroquinolones. CONCLUSIONSATR is an adverse event that can occur in patients over 60 years of age treated with fluoroquinolones, so an adequate risk-benefit assessment should be carried out in this population, especially in the presence of associated risk factors.</abstract><doi>10.1016/j.reuma.2019.08.004</doi></addata></record>
fulltext fulltext
identifier EISSN: 2173-5743
ispartof Reumatologia clinica, 2021, Vol.17 (3), p.141-143
issn 2173-5743
language eng ; spa
recordid cdi_proquest_miscellaneous_2311639282
source Elsevier
title Achilles Tendon Rupture Associated with the Use of Fluoroquinolones in Patients Over 60 Years of AGE: Experience From a Single Tertiary Centre
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-13T08%3A41%3A06IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest&rft_val_fmt=info:ofi/fmt:kev:mtx:book&rft.genre=unknown&rft.atitle=Achilles%20Tendon%20Rupture%20Associated%20with%20the%20Use%20of%20Fluoroquinolones%20in%20Patients%20Over%2060%20Years%20of%20AGE:%20Experience%20From%20a%20Single%20Tertiary%20Centre&rft.jtitle=Reumatologia%20clinica&rft.au=Briones-Figueroa,%20Andrea&rft.date=2021-03-01&rft.volume=17&rft.issue=3&rft.spage=141&rft.epage=143&rft.pages=141-143&rft.eissn=2173-5743&rft_id=info:doi/10.1016/j.reuma.2019.08.004&rft_dat=%3Cproquest%3E2311639282%3C/proquest%3E%3Cgrp_id%3Ecdi_FETCH-proquest_miscellaneous_23116392823%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=2311639282&rft_id=info:pmid/&rfr_iscdi=true