Nutrition in Chronic Liver Disease

• Published in: Current treatment options in gastroenterology 2019-12, Vol.17 (4), p.602-618
• Main Authors: Reddy, Yala Kirthi, Maliakkal, Benedict, Agbim, Uchenna
• Format: Article
• Language: English
• Subjects: Gastroenterology; Medicine & Public Health; Nutrition and Obesity (O Pickett-Blakely; Section Editor; Topical Collection on Obesity and Nutrition
• ISSN: 1092-8472; 1534-309X
• DOI: 10.1007/s11938-019-00252-3

Purpose of review Malnutrition is a common finding in patients with chronic advanced liver disease (CLD) and is an important prognostic predictor for morbidity and mortality. This review aims to summarize the latest evidence-based guidelines and expert opinion regarding diagnosing malnutrition in patients with CLD and providing optimal solutions. Recent findings In addition to diet, evidence demonstrates sarcopenia and frailty are emerging concepts critical to outcomes in those with CLD. Thus, adequate assessment of nutritional status incorporates the interplay of nutrient intake, sarcopenia, and frailty. Summary Addressing malnutrition in patients with CLD requires understanding the multifactorial mechanisms contributing to nutritional deficiencies, but also careful assessment of functional capacity. Interventions mitigating or reversing sarcopenia and frailty are equally important to nutritional supplementation. While the latency period between compensated and decompensated cirrhosis provides a good window for fruitful interventions, we believe providers need to be vigilant early on the course of CLD to maximize nutritional gains and halt muscle loss.