Risk factors for recurrence in cutaneous squamous cell carcinoma after Mohs micrographic surgery: A retrospective review of 237 Asian patients

Even after complete removal with Mohs micrographic surgery (MMS), cutaneous squamous cell carcinoma (cSCC) may recur; however, information about risk factors for recurrence in Asian patients is limited. This retrospective study reviewed cSCC patients treated with MMS at a single tertiary referral ce...

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Bibliographic Details
Published in:Journal of dermatology 2020-01, Vol.47 (1), p.72-77
Main Authors: Oh, Yeongjoo, Kim, Jemin, Zheng, Zhenlong, Kim, Sang Kyem, Chung, Kee Yang, Roh, Mi Ryung
Format: Article
Language:English
Subjects:
Cryotherapy
cutaneous squamous cell carcinoma
Diabetes mellitus
Medical prognosis
Metastases
Metastasis
Mohs micrographic surgery
prognostic factor
recurrence
Risk factors
Skin cancer
Squamous cell carcinoma
Surgery
Transplantation
validity
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Summary:Even after complete removal with Mohs micrographic surgery (MMS), cutaneous squamous cell carcinoma (cSCC) may recur; however, information about risk factors for recurrence in Asian patients is limited. This retrospective study reviewed cSCC patients treated with MMS at a single tertiary referral center from 2000 to 2017. Two hundred and thirty‐seven patients were included and 36 showed recurrence (20 with local recurrence, 16 with distant metastasis). History of organ transplantation, diabetes, other malignancies and poorly differentiated histology correlated with cSCC recurrence. History of organ transplantation and cryotherapy at the cSCC site were related to higher local recurrence rates, and poor differentiation related to higher distant metastasis in Asian cSCC patients treated with MMS.
ISSN:0385-2407
1346-8138
DOI:10.1111/1346-8138.15129