Dual-energy computed tomography for evaluation of breast cancer: value of virtual monoenergetic images reconstructed with a noise-reduced monoenergetic reconstruction algorithm

Purpose To evaluate the image quality and lesion visibility of virtual monoenergetic images (VMIs) reconstructed using a new monoenergetic reconstruction algorithm (nMERA) for evaluation of breast cancer. Materials and methods Forty-two patients with 46 breast cancers who underwent 4-phasic breast c...

Full description

Saved in:
Bibliographic Details
Published in:Japanese journal of radiology 2020-02, Vol.38 (2), p.154-164
Main Authors: Okada, Kanako, Matsuda, Megumi, Tsuda, Takaharu, Kido, Teruhito, Murata, Akihiro, Nishiyama, Hikaru, Nishiyama, Kanako, Yamasawa, Haruna, Kamei, Yoshiaki, Kurata, Mie, Fukushima, Mana, Kitazawa, Riko, Mochizuki, Teruhito
Format: Article
Language:English
Subjects:
Algorithms
Breast cancer
Computed tomography
Image enhancement
Image quality
Image reconstruction
Imaging
Lesions
Medical imaging
Medicine
Medicine & Public Health
Noise
Nuclear Medicine
Original Article
Radiology
Radiotherapy
Tomography
Tumors
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Purpose To evaluate the image quality and lesion visibility of virtual monoenergetic images (VMIs) reconstructed using a new monoenergetic reconstruction algorithm (nMERA) for evaluation of breast cancer. Materials and methods Forty-two patients with 46 breast cancers who underwent 4-phasic breast contrast-enhanced computed tomography (CT) using dual-energy CT (DECT) were enrolled. We selected the peak enhancement phase of the lesion in each patient. The selected phase images were generated by 120-kVp-equivalent linear blended (M120) and monoenergetic reconstructions from 40 to 80 keV using the standard reconstruction algorithm (sMERA: 40, 50, 60, 70, 80) and nMERA (40 +, 50 +, 60 +, 70 +, 80 +). The contrast-to-noise ratio (CNR) was calculated and objectively analyzed. Two independent readers subjectively scored tumor visibility and image quality each on a 5-point scale. Results The CNR at 40 + and tumor visibility scores at 40 + and 50 + were significantly higher than those on M120. The CNR at 50 + was not significantly different from that on M120. However, the overall image quality score at 40 + was significantly lower than that at 50 + and on M120 (40 + vs M120, P  
ISSN:1867-1071
1867-108X
DOI:10.1007/s11604-019-00897-1