Takotsubo syndrome: an overview of pathophysiology, diagnosis and treatment with emphasis on cancer patients

Takotsubo syndrome is a disease of great clinical importance that remains underdiagnosed. It is a form of acute heart failure characterized by a transient wall motion abnormality of the left ventricular apex typically triggered by emotional or physical stress. Takotsubo syndrome is commonly associat...

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Bibliographic Details
Published in:Heart failure reviews 2019-11, Vol.24 (6), p.833-846
Main Authors: da Silva Costa, Isabela Bispo Santos, Figueiredo, Clara Salles, Fonseca, Silvia Moulin Ribeiro, Bittar, Cristina Salvadori, de Carvalho Silva, Carolina Maria Domingues, Rizk, Stéphanie Itala, Filho, Roberto Kalil, Hajjar, Ludhmila Abrahão
Format: Article
Language:English
Subjects:
Acute Disease
Adolescent
Adult
Aged
Aged, 80 and over
Cancer
Cardiology
Congestive heart failure
Early Diagnosis
Female
Heart Failure - diagnosis
Heart Failure - mortality
Heart Failure - physiopathology
Heart Ventricles - physiopathology
Humans
Male
Medicine
Medicine & Public Health
Middle Aged
Neoplasms - complications
Neoplasms - epidemiology
Patients
Prevalence
Prognosis
Stress, Psychological - complications
Stress, Psychological - epidemiology
Stroke Volume - physiology
Takotsubo Cardiomyopathy - diagnosis
Takotsubo Cardiomyopathy - mortality
Takotsubo Cardiomyopathy - physiopathology
Takotsubo Cardiomyopathy - therapy
Ventricle
Ventricular Remodeling - physiology
Young Adult
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Summary:Takotsubo syndrome is a disease of great clinical importance that remains underdiagnosed. It is a form of acute heart failure characterized by a transient wall motion abnormality of the left ventricular apex typically triggered by emotional or physical stress. Takotsubo syndrome is commonly associated with cancer and results in poor outcomes. Therefore, early recognition and prompt therapy are essential to improve prognosis. The aim of this manuscript is to review the consequences of the association between cancer and Takotsubo to summarize the available evidence to guide physicians to improve the management of these patients.
ISSN:1382-4147
1573-7322
DOI:10.1007/s10741-019-09813-1