Association of dietary components with dyslipidemia and low-grade inflammation biomarkers in adults with heterozygous familial hypercholesterolemia from different countries

• Published in: European journal of clinical nutrition 2019-12, Vol.73 (12), p.1622-1625
• Main Authors: Antoniazzi, Luiza, Arroyo-Olivares, Raquel, Bittencourt, Marcio S., Tada, Mauricio Teruo, Lima, Isabella, Jannes, Cinthia E., Krieger, Jose E., Pereira, Alexandre C., Quintana-Navarro, Gracia, Muñiz-Grijalvo, Ovidio, Díaz-Díaz, José Luís, Zambón, Daniel, Mata, Pedro, Santos, Raul D.
• Format: Article
• Language: English
• Subjects: 692/163/2743/2099; 692/53; Adults; Apolipoprotein B; Apolipoproteins; Arteriosclerosis; Associations; Atherosclerosis; Biomarkers; Brief Communication; C-reactive protein; Carbohydrates; Cholesterol; Clinical Nutrition; Development and progression; Diet therapy; Dyslipidemia; Dyslipidemias; Epidemiology; Fats; Fatty acids; Health aspects; Hypercholesterolemia; Internal Medicine; Lipids; Low density lipoprotein; Low fat diet; Medicine; Medicine & Public Health; Metabolic Diseases; Metabolic disorders; Physiological aspects; Public Health; Saturated fatty acids; Trans fatty acids
• ISSN: 0954-3007; 1476-5640
• DOI: 10.1038/s41430-019-0529-3

The association of components of a low saturated fat (SFA) and of a Mediterranean diet was tested with atherosclerosis biomarkers in 190 familial hypercholesterolemia adults (FH) from Brazil (BR) and Spain (SP). Median blood LDL-C, Apolipoprotein B (apoB), and C reactive protein (hs-CRP) concentrations were higher in BR than in SP: 179.0 vs.161 mg/dL; 141 vs. 103 mg/dL; and 1.6 vs. 0.8 mg/L respectively (all p