A man with weak limbs

Axial T1 weighted MRI of the brain with intravenous gadolinium contrast medium shows a heterogeneous rim enhancing lesion (red arrow) at the left frontal lobe, with mixed enhancing solid and hypointense cystic components (white arrow) Definitive diagnosis is by histological assessment. Depending on...

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Bibliographic Details
Published in:BMJ (Online) 2019-11, Vol.367, p.l6233-l6233
Main Authors: Lee, Shing Fung, Yip, Pui Lam, Wong, Frank Chi Sing
Format: Article
Language:English
Subjects:
Antineoplastic Agents, Alkylating - administration & dosage
Autonomy
Brain cancer
Brain Neoplasms - diagnosis
Brain Neoplasms - physiopathology
Brain Neoplasms - therapy
Brain research
Cancer therapies
Chemotherapy
Cognitive ability
Craniotomy
Epilepsy
Frontal lobe
Gadolinium
Glioblastoma - diagnosis
Glioblastoma - physiopathology
Glioblastoma - therapy
Glioma
Humans
Intravenous administration
Lesions
Magnetic Resonance Imaging
Male
Medical research
Mens health
Metastases
Metastasis
Middle Aged
Muscle Weakness - diagnostic imaging
Muscle Weakness - physiopathology
Neuroimaging
Neurological complications
NMR
Nuclear magnetic resonance
Patients
Quality of life
Radiation therapy
Radiotherapy
Temozolomide - administration & dosage
Treatment Outcome
Tumors
Citations: Items that this one cites
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Description
Summary:Axial T1 weighted MRI of the brain with intravenous gadolinium contrast medium shows a heterogeneous rim enhancing lesion (red arrow) at the left frontal lobe, with mixed enhancing solid and hypointense cystic components (white arrow) Definitive diagnosis is by histological assessment. Depending on tumour location, patients may have motor, speech, and/or cognitive impairment, focal neurological deficit, epilepsy, and/or features of high intracranial pressure.6 Patients may experience reduced functional independence and autonomy in daily living, fatigue, depression, and change in personality, emotion, or behaviour.67 3. Offer multidisciplinary management to relieve symptoms, improve function, survival, and quality of life; and assist with self care, financial management, and transportation.8 Consider total resection, radiotherapy, chemotherapy, and low intensity alternating electrical field therapy on a case-by-case basis.91011 Learning point Typically, gliomas manifest as solitary lesions and brain metastasis as multiple lesions.
ISSN:0959-8138
1756-1833
DOI:10.1136/bmj.l6233