Extensive postoperative subdural fluid volume affects the onset of chronic subdural hematoma after unruptured aneurysmal clipping surgery

• Published in: Clinical neurology and neurosurgery 2019-12, Vol.187, p.105533-105533, Article 105533
• Main Authors: Murakami, Toshiharu, Nakagawa, Ichiro, Park, Hun Soo, Kotsugi, Masashi, Takamura, Yoshiaki, Takeshima, Yasuhiro, Matsuda, Ryosuke, Nishimura, Fumihiko, Yamada, Shuichi, Motoyama, Yasushi, Su Park, Young, Nakase, Hiroyuki
• Format: Article
• Language: English
• Subjects: Age; Aneurysm; Aneurysmal clipping surgery; Aneurysms; Arachnoid; Arachnoid-plasty procedure; Blood; Brain; Chronic subdural hematoma; Communications systems; Diabetes; Dura mater; Gender; Hematoma; Hypertension; Medical imaging; Meninges; Neurology; Patients; Regression analysis; Risk factors; Subdural fluid volume; Surgery
• ISSN: 0303-8467; 1872-6968
• DOI: 10.1016/j.clineuro.2019.105533

•Evaluation of subdural fluid volume (SFV) and CSDH onset after aneurysmal surgery.•SFV was significantly larger in the CSDH group.•Intraoperative arachnoid-plasty neither reduced SFV nor the onset of CSDH.•Multivariate regression analysis revealed extensive SFV associated with CSDH onset. To evaluate risk factors associated with chronic subdural hematoma (CSDH) onset after clipping surgery for unruptured intracranial aneurysm, and determine whether intraoperative conventional arachnoid-plasty (ARP) can suppress the CSDH onset by reducing subdural fluid volume. We retrospectively evaluated 217 patients who underwent surgical clipping at our institution from 2012 to 2018. Risk and predictive factors for symptomatic CSDH development including clinical characteristics, postoperative subdural fluid volume, Hounsfield unit (HU) value of subdural fluid density evaluated by CT and the effect of conventional ARP were compared between CSDH and non-CSDH groups. Of 217 patients who underwent surgical clipping for anterior circulation aneurysm, 209 were included in this study. Among whom, postoperative CSDH, required burr irrigation, occurred in 12 (5.7%). Mean age was significantly higher in the CSDH group (70 ± 8 years) than in the non-CSDH group (64 ± 11 years, p = 0.03). Subdural fluid volumes on postoperative day (POD)1, POD8 and POD30 were significantly larger in the CSDH group than in the non-CSDH group (38.4 ± 33.5 cm3, 54.8 ± 36.3 cm3, 77.2 ± 36.1 cm3 vs 10.0 ± 7.7 cm3, 16.1 ± 12.8 cm3, 14.0 ± 17.5 cm3, p < 0.001, respectively). However, intraoperative conventional ARP did not reduce postoperative subdural fluid volume nor suppress onset of CSDH. Multivariate logistic regression analysis revealed extensive subdural fluid volume as the only risk factor independently associated with CSDH development. In this study, postoperative large subdural fluid volume represented an independent risk factor associated with the incidence of CSDH after unruptured aneurysmal clipping. Reducing subdural fluid volume strategy could suppress the onset of CSDH after surgery.