Genomic characterization and comparative analysis of Leptospira kirschneri serogroup Grippotyphosa UC5/2011, a strain isolated after mare abortion: Implications for genital animal leptospirosis

•Leptospira kirschneri strain genome associated with the abortion of a Brazilian mare.•The UC5/2011 strain was most likely imported from Europe.•This study has implications for better understanding of genital leptospirosis. The genome of a Brazilian strain of Leptospira kirschneri serogroup Grippoty...

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Bibliographic Details
Published in:Comparative immunology, microbiology and infectious diseases microbiology and infectious diseases, 2019-06, Vol.64, p.7-9
Main Authors: Jaeger, Lauren H., Moreno, Luisa Z., Kremer, Frederico S., Dellagostin, Odir A., Moreno, Andrea M., Lilenbaum, Walter
Format: Article
Language:English
Subjects:
Abortion
Antimicrobial resistance
Comparative analysis
Genital leptospirosis
Genomes
Leptospira
Leptospira kirschneri
Leptospirosis
Livestock
Next generation sequencing
Virulence
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Summary:•Leptospira kirschneri strain genome associated with the abortion of a Brazilian mare.•The UC5/2011 strain was most likely imported from Europe.•This study has implications for better understanding of genital leptospirosis. The genome of a Brazilian strain of Leptospira kirschneri serogroup Grippotyphosa isolated from a mare post-abortion was sequenced and analyzed. High symmetrical identity and few structural differences were found when compared with a European strain of the same serogroup, L. kirschneri serovar Valbuzzi strain 200702274. Genes associated with virulence and antimicrobial resistance were found. Knowledge of the virulence evolution of Leptospira remains limited, especially in diseases of the reproductive sphere. We highlight the importance of virulence studies in the sphere of genital leptospirosis.
ISSN:0147-9571
1878-1667
DOI:10.1016/j.cimid.2019.01.019