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Post-operative abdominal infections: epidemiology, operational definitions, and outcomes
Postoperative abdominal infections are an important and heterogeneous health challenge in intensive care units (ICU) and encompass postoperative infectious processes developing within the abdominal cavity that may be caused by either bacterial or fungal pathogens. In this narrative review, we discus...
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Published in: | Intensive care medicine 2020-02, Vol.46 (2), p.163-172 |
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creator | Bassetti, Matteo Eckmann, Christian Giacobbe, Daniele Roberto Sartelli, Massimo Montravers, Philippe |
description | Postoperative abdominal infections are an important and heterogeneous health challenge in intensive care units (ICU) and encompass postoperative infectious processes developing within the abdominal cavity that may be caused by either bacterial or fungal pathogens. In this narrative review, we discuss postoperative bacterial and fungal abdominal infections, covering also multidrug-resistant (MDR) pathogens. We also cover clinically preeminent aspects such as the definition of postoperative abdominal infections, which still remains difficult owing to their heterogeneity in patient characteristics, clinical presentation, ecology and antimicrobial treatment. With regard to treatment, modifiable factors such as source control and antimicrobial therapy play a key role in influencing the prognosis of postoperative abdominal infections, but several conditions may hamper their correct application; thus efforts should necessarily be devoted towards improving their appropriateness and timing. Hot topics regarding the characteristics and management of postoperative abdominal infections are discussed in this narrative review. |
doi_str_mv | 10.1007/s00134-019-05841-5 |
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subjects | Abdomen Abscess Anesthesiology Antifungal agents Antiinfectives and antibacterials Antimicrobial agents Care and treatment Critical Care Medicine Drug resistance in microorganisms Emergency Medicine Epidemiology Fungi Health aspects Heterogeneity Hospitals Infection Infections Intensive Intensive care units Medicine Medicine & Public Health Methicillin Multidrug resistance Narrative Review Pain Medicine Pathogens Pediatrics Pneumology/Respiratory System Severe infections in the critically ill |
title | Post-operative abdominal infections: epidemiology, operational definitions, and outcomes |
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