Forensic effectiveness and genetic distribution of 23 autosomal STRs included in Verifiler PlusTM multiplex in a population sample from Madhya Pradesh, India

• Published in: International journal of legal medicine 2020-07, Vol.134 (4), p.1327-1328
• Main Authors: Shrivastava, Pankaj, Kaitholia, Kamlesh, Kumawat, R. K., Dixit, Shivani, Dash, Hirak Ranjan, Srivastava, Ankit, Baroniya, Yash, Mishra, Aditi, Kushwaha, Pushpesh, Rana, Manisha, Dixit, Akansha, Sarawagi, Tanya, Bhatt, Alay, Sharma, Harsh, Sinha, Moumita, Chaubey, Gyaneshwer
• Format: Article
• Language: English
• Subjects: Forensic Medicine; Markers; Medical Law; Medicine; Medicine & Public Health; Multiplexing; Polymorphism; Population; Population Data; Population genetics
• ISSN: 0937-9827; 1437-1596
• DOI: 10.1007/s00414-019-02172-4

We report here the first ever global study on genetic polymorphism using a Verifiler Plus TM autosomal STR multiplex system. The study evaluated genetic characteristics of 23 autosomal STRs in 200 unrelated residents of Guna district of Madhya Pradesh, India. Allele frequencies and forensic parameters are reported. Population comparison analysis was also performed using NJ tree and PCA plot. Penta E marker showed highest power of discrimination (0.938) among all 23 studied markers. The study also presents the first ever global forensic assessment in Indian population on D6S1043 marker (PD 0.937). The results demonstrated that all the 23 markers were highly polymorphic and the Verifiler Plus TM kit is suitable for forensic purposes in Indian population.