CaRdiac Arrest Survival Score (CRASS) — A tool to predict good neurological outcome after out-of-hospital cardiac arrest

The aim of this study was to develop a score to predict the outcome for patients brought to hospital following out-of-hospital cardiac arrest (OHCA). All patients recorded in the German Resuscitation Registry (GRR) who suffered OHCA 2010–2017, who had ROSC or ongoing CPR at hospital admission were i...

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Bibliographic Details
Published in:Resuscitation 2020-01, Vol.146, p.66-73
Main Authors: Seewald, S., Wnent, J., Lefering, R., Fischer, M., Bohn, A., Jantzen, T., Brenner, S., Masterson, S., Bein, B., Scholz, J., Gräsner, J.T.
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
CaRdiac Arrest Survival Score
Cardiopulmonary Resuscitation - methods
Cardiopulmonary Resuscitation - statistics & numerical data
Female
German Resuscitation Registry
Germany - epidemiology
Humans
Male
Middle Aged
Nervous System Diseases - diagnosis
Nervous System Diseases - epidemiology
Nervous System Diseases - etiology
Nervous System Diseases - prevention & control
Out of hospital cardiac arrest
Out-of-Hospital Cardiac Arrest - complications
Out-of-Hospital Cardiac Arrest - epidemiology
Out-of-Hospital Cardiac Arrest - therapy
Patient Discharge - statistics & numerical data
Predictive Value of Tests
Prognosis
Registries - statistics & numerical data
Retrospective Studies
Risk Factors
Survival Analysis
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Summary:The aim of this study was to develop a score to predict the outcome for patients brought to hospital following out-of-hospital cardiac arrest (OHCA). All patients recorded in the German Resuscitation Registry (GRR) who suffered OHCA 2010–2017, who had ROSC or ongoing CPR at hospital admission were included. The study population was divided into development (2010–2016: 7985) and validation dataset (2017: 1806). Binary logistic regression analysis was used to derive the score. The probability of hospital discharge with good neurological outcome was defined as 1/(1 + e−X), where X is the weighted sum of independent variables. The following variables were found to have a significant positive (+) or negative (−) impact: age 61–70 years (−0·5), 71–80 (−0·9), 81–90 (−1·3) and > = 91 (−2·3); initial PEA (−0·9) and asystole (−1·4); presumable trauma (−1·1); mechanical CPR (−0·3); application of adrenalin > 0 − 
ISSN:0300-9572
1873-1570
DOI:10.1016/j.resuscitation.2019.10.036