Insights on the current status and advancement of diabetes mellitus type 2 and to avert complications: An overview

Type 2 diabetes mellitus (T2DM) is an endocrine metabolic disorder, occurring worldwide due to aging, advancement in lifestyle by modernization. T2DM is characterized by higher levels of glucose in the blood due to unresponsive secretion of pancreatic insulin and insulin activity or altogether. T2DM...

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Bibliographic Details
Published in:Biotechnology and applied biochemistry 2020-11, Vol.67 (6), p.920-928
Main Authors: Chung, Ill‐Min, Rajakumar, Govindasamy, Subramanian, Umadevi, Venkidasamy, Baskar, Khanna, Venkatesan Gopiesh, Thiruvengadam, Muthu
Format: Article
Language:English
Subjects:
Aging
antiglycemic agents
Beta cells
completions
Complications
Diabetes
Diabetes mellitus
Diabetes mellitus (non-insulin dependent)
diabetes mellitus type 2
Insulin
Insulin resistance
Metabolic disorders
Modernization
Pancreas
Pathophysiology
Physical activity
treatment strategies
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Summary:Type 2 diabetes mellitus (T2DM) is an endocrine metabolic disorder, occurring worldwide due to aging, advancement in lifestyle by modernization. T2DM is characterized by higher levels of glucose in the blood due to unresponsive secretion of pancreatic insulin and insulin activity or altogether. T2DM is regarded as a powerful genetic susceptible disease that leads to high risk with insulin resistance and β‐cell dysfunction. To manage and overcome type 2 diabetes, physical activity, diet strategies, and other therapeutic medications along with usage of antiglycemic agents are developed and attempted appropriately. In the present review, attention has been focused on the understanding of T2DM outcomes, complications with possible management strategies, and pathophysiology of T2DM. Further, a detailed note on antiglycemic agents in use and other possible drugs of choice was discussed in the light of current preventive strategies are presented in this review. Treatment strategies of type 2 diabetes.
ISSN:0885-4513
1470-8744
DOI:10.1002/bab.1853