Carbon fibers coated with urchin-like copper sulfide for nonenzymatic voltammetric sensing of glucose

• Published in: Mikrochimica acta (1966) 2019-12, Vol.186 (12), p.807-807, Article 807
• Main Authors: Keerthi, Murugan, Mutharani, Bhuvanenthiran, Chen, Shen-Ming, Ranganathan, Palraj
• Format: Article
• Language: English
• Subjects: Analytical Chemistry; Characterization and Evaluation of Materials; Chemistry; Chemistry and Materials Science; Dextrose; Electric properties; Electrical conductivity; Enzymes; Glucose; Microengineering; Nanochemistry; Nanotechnology; Original Paper; Polysaccharides; Sulfides
• ISSN: 0026-3672; 1436-5073
• DOI: 10.1007/s00604-019-3915-6

Urchin-like CuS was grown on xanthan gum-derived carbon nanofibers to obtain a sensor for enzyme-free electrochemical sensing of glucose. The unique nanostructure of the sensor provides a large specific surface, more electrocatalytically active sites, and high electrical conductivity. The voltammetric response to glucose, best measured at around 57 mV (vs. Ag/AgCl (E/V)) in 0.1 M NaOH solution, covers two linear ranges, one from 0.1–125 μM, another from 0.16 to 1.2 mM. The sensitivity is quite high (23.7 μA mM −1  cm −2 ), and the detection limit is low (19 nM at S/ N  = 3). The sensor has high selectivity against potentially interfering molecules such as fructose, appreciable operational stability, excellent durability, and good repeatability (with relative standard deviations of 2.3%). It was successfully applied to the determination of glucose in diluted serum samples. Graphical abstract Schematic representation of electrochemical detection of glucose based on the use of a screen printed carbon electrode (SPCE) modified with CuS and xanthan gum-derived carbon nanofibers (XGCNFs).