Masticatory Capacity and Mortality: The Preventive and Clinical Investigation Center (IPC) Cohort Study

• Published in: Journal of dental research 2020-02, Vol.99 (2), p.152-158
• Main Authors: Darnaud, C., Thomas, F., Danchin, N., Boutouyrie, P., Bouchard, P.
• Format: Article
• Language: English
• Subjects: Cancer; Cardiovascular diseases; Cohort analysis; Dental calculus; Dental plaque; Dentistry; Mastication; Mortality; Premolars; Statistical analysis; Teeth
• ISSN: 0022-0345; 1544-0591
• DOI: 10.1177/0022034519889021

Poor oral health (OH) has been associated with mortality, but the association between OH components and mortality remains imprecise. The present observational study aimed to investigate if there is an association between oral masticatory efficiency and cardiovascular (CV) mortality in a large French subject cohort. The study was based on a cohort of 85,830 subjects aged between 16 and 94 y at recruitment. The follow-up extended from 2001 to 2014 and the mean follow-up was 8.06 ± 2.73 y. The number of deaths totaled 1,670. Full-mouth examinations were performed. Dental plaque, dental calculus, gingival inflammation, missing teeth, and masticatory units were recorded. Masticatory units represent the number of natural or prosthetic opposing premolars and molar pairs and can be considered an accurate indicator for masticatory efficiency. Causes of death were ascertained from death certificates. Cox regression analyses were used to calculate hazard ratios (HRs). In the fully adjusted model, the number of masticatory units