Optimization of low-energy electron beam production for superficial cancer treatments by Monte Carlo code

Context: Low energy electron beam has been being used widely for superficial cancer treatments. In the current study a design for production of very low energy electron beam, by different thickness of Perspex spoilers, is presented that may be used for skin cancer. Aims: MCNPX Monte Carlo code was u...

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Bibliographic Details
Published in:Journal of cancer research and therapeutics 2019-07, Vol.15 (3), p.475-479
Main Authors: Akbarpoor, Rana, Khaledi, Navid, Wang, Xufei, Samiei, Farhad
Format: Article
Language:English
Subjects:
Algorithms
Aluminum
Cancer therapies
Cancer treatment
Electron beam computed tomography
Electrons
Energy
Humans
Monte Carlo Method
Monte Carlo methods
Monte Carlo simulation
Neoplasms - diagnosis
Neoplasms - radiotherapy
Particle Accelerators
Radiotherapy Dosage
Radiotherapy Planning, Computer-Assisted - methods
Skin
Skin cancer
Skin Neoplasms - diagnosis
Skin Neoplasms - radiotherapy
Studies
Tumors
X-rays
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Summary:Context: Low energy electron beam has been being used widely for superficial cancer treatments. In the current study a design for production of very low energy electron beam, by different thickness of Perspex spoilers, is presented that may be used for skin cancer. Aims: MCNPX Monte Carlo code was used for modeling and simulations in the current study. An energy spoiler Perspex was modeled for degrading 4 MeV electron beam of Varian 2300 CD Linac. Materials and Methods: The thicknesses of 3, 7, and 10 mm were applied before electron applicator at a distance of 42 cm from phantom surface. Dosimetric properties of new electron beams including Rp, Dmax, E0, as well as the penumbra of the beam were investigated. Results: For the 3 mm spoiler, the superficial beam output decreased to 77%, and the Dmax, R90, R50, and RP were shifted to the depths of 4, 6, 9, and 12 mm, respectively. While for 10 mm filter the results were 5.2, 3.0 and 5.0 mm for R90, R50, and Rp, respectively. In addition, the surface dose was 93% and the Dmax was shifted to the depth of 1mm for the 10mm Perspex spoiler slab. Conclusions: The presented beam provides a novel surface dose, Dmax, and RP which can be applicable for treatment of skin cancers with minimum dose to the beyond normal tissues.
ISSN:0973-1482
1998-4138
DOI:10.4103/jcrt.JCRT_203_18