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Clinical and echocardiographic features of paradoxical low-flow and normal-flow severe aortic stenosis patients with concomitant mitral regurgitation

Mitral regurgitation (MR) coexists in a significant proportion of patients with severe aortic stenosis (AS), and portends inferior therapeutic outcomes. In severe AS, MR is thought to contribute to a low-flow state by decreasing forward stroke volume. We investigated concomitant MR on the clinical a...

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Bibliographic Details
Published in:The International Journal of Cardiovascular Imaging 2020-03, Vol.36 (3), p.441-446
Main Authors: Ngiam, Jinghao Nicholas, Chew, Nicholas, Teng, Rebecca, Kochav, Jonathan D., Kochav, Stephanie M., Tan, Benjamin Yong-Qiang, Sim, Hui Wen, Sia, Ching-Hui, Kong, William K. F., Tay, Edgar Lik Wui, Yeo, Tiong-Cheng, Poh, Kian-Keong
Format: Article
Language:English
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Summary:Mitral regurgitation (MR) coexists in a significant proportion of patients with severe aortic stenosis (AS), and portends inferior therapeutic outcomes. In severe AS, MR is thought to contribute to a low-flow state by decreasing forward stroke volume. We investigated concomitant MR on the clinical and echocardiographic features of patients with “paradoxical” low-flow (PLF) and normal-flow (NF) severe AS. Clinical and echocardiographic profiles of 886 consecutive patients with index echocardiographic diagnosis of severe AS (AVA 
ISSN:1569-5794
1573-0743
1875-8312
DOI:10.1007/s10554-019-01735-1