The True Story on Deficiencies After Sleeve Gastrectomy: Results of a Double-Blind RCT

Background Since a few years, the laparoscopic sleeve gastrectomy (SG) has become the most performed bariatric operation worldwide. However, as with all bariatric procedures, SG also leads to vitamin and mineral deficiencies post-operatively and standard multivitamin supplements are probably not suf...

Full description

Saved in:
Bibliographic Details
Published in:Obesity surgery 2020-04, Vol.30 (4), p.1280-1290
Main Authors: Heusschen, Laura, Schijns, Wendy, Ploeger, Nadine, Deden, Laura N., Hazebroek, Eric J., Berends, Frits J., Aarts, Edo O.
Format: Article
Language:English
Subjects:
Dietary minerals
Dietary Supplements
Double-blind studies
Gastrectomy
Humans
Medicine
Medicine & Public Health
Netherlands - epidemiology
Obesity, Morbid - surgery
Original Contributions
Surgery
Vitamin B
Vitamin D
Vitamins
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Background Since a few years, the laparoscopic sleeve gastrectomy (SG) has become the most performed bariatric operation worldwide. However, as with all bariatric procedures, SG also leads to vitamin and mineral deficiencies post-operatively and standard multivitamin supplements are probably not sufficient. Objective The present study evaluates the effectiveness of a specialized multivitamin supplement for SG patients (WLS Optimum 1.0, FitForMe, Rotterdam, the Netherlands), compared to a standard multivitamin supplement (sMVS). Design A double-blind randomized controlled trial was performed. For 12 months, patients in the intervention group received WLS Optimum, containing elevated doses of multiple vitamins and minerals. Patients in the control group were provided with sMVS, containing 100% of the recommended dietary allowance. Results In total, 139 patients were available for analysis (WLS Optimum, n  = 69; sMVS, n  = 70). Intention-to-treat analyses revealed more folic acid deficiencies and higher serum vitamin B1 levels in the WLS Optimum group. Per protocol analyses showed that in patients using WLS Optimum, serum folic acid and vitamin B1 levels were higher, serum PTH levels were lower, and only one patient (2.6%) was anemic compared to 11 patients (17.5%) using a sMVS ( p  
ISSN:0960-8923
1708-0428
DOI:10.1007/s11695-019-04252-1