Frequency of non‐motor symptoms and their impact on the quality of life in patients with Parkinson's disease: a prospective descriptive case series

Aim In this study, we aimed to show non‐motor symptoms (NMS), in addition to motor symptoms, in the foreground of idiopathic Parkinson's disease (IPD). We also examined the prevalence of dopamine dysregulation syndrome, which can be evaluated based on NMS, its risk factors, and its effects on q...

Full description

Saved in:
Bibliographic Details
Published in:Psychogeriatrics 2020-03, Vol.20 (2), p.206-211
Main Authors: Gulunay, Aydin, Cakmakli, Gul Y., Yon, Mehmet I., Ulusoy, Ersin K., Karakoc, Mehmet
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Basal ganglia
Brain diseases
Central nervous system diseases
Cognition Disorders - complications
Cognitive ability
Dopamine
Dopamine - metabolism
dopamine dysregulation syndrome
Female
Humans
idiopathic Parkinson's disease
Male
Middle Aged
Movement disorders
Neurodegenerative diseases
non‐motor symptoms
Parkinson Disease - complications
Parkinson Disease - psychology
Parkinson's disease
Patients
Prospective Studies
Quality of life
Quality of Life - psychology
Questionnaires
Risk factors
Severity of Illness Index
Sleep
Sleep Wake Disorders - complications
Surveys and Questionnaires
Young Adult
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Aim In this study, we aimed to show non‐motor symptoms (NMS), in addition to motor symptoms, in the foreground of idiopathic Parkinson's disease (IPD). We also examined the prevalence of dopamine dysregulation syndrome, which can be evaluated based on NMS, its risk factors, and its effects on quality of life (QOL) by using various scales and questionnaires. Methods In total, 75 patients with IPD (46 men, 29 women) who attend the outpatient neurology clinic of our hospital were included in the study. The motor symptoms and NMS of IPD were examined. The severity of parkinsonism was evaluated with the Unified Parkinson's Disease Rating Scale and the Hoehn and Yahr scale. Cognitive tests, the NMS questionnaire, the Parkinson's Disease Sleep Scale, and the Dopamine Dysregulation Syndrome‐Patient and Caregiver Inventory were used to identify NMS. The 39‐item Parkinson's Disease Questionnaire evaluated QOL. Results We observed a significant increase in scores on the tests assessing NMS, specifically the Parkinson's Disease Questionnaire, NMS questionnaire, Parkinson's Disease Sleep Scale, and Geriatric Depression Scale (P 
ISSN:1346-3500
1479-8301
DOI:10.1111/psyg.12489