Vitamin D metabolism in dogs and cats and its relation to diseases not associated with bone metabolism

Due to the presence of receptors in the cells of numerous body tissues, vitamin D is associated with several physiological functions that go beyond calcium and phosphorus homoeostasis and control of bone metabolism in the body. In humans, several studies have associated lower vitamin D concentration...

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Bibliographic Details
Published in:Journal of animal physiology and animal nutrition 2020-01, Vol.104 (1), p.322-342
Main Authors: Zafalon, Rafael V. A., Risolia, Larissa W., Pedrinelli, Vivian, Vendramini, Thiago H. A., Rodrigues, Roberta B. A., Amaral, Andressa R., Kogika, Marcia M., Brunetto, Marcio A.
Format: Article
Language:English
Subjects:
1,25(OH)2D
25(OH)D
Autoimmune diseases
Bone turnover
calcidiol
Calciferol
calcitriol
Calcium
Cardiovascular diseases
cholecalciferol
Coronary artery disease
Dogs
Heart diseases
hypovitaminosis D
Infectious diseases
Metabolism
Phosphorus
Receptors
Tissues
Veterinary medicine
Vitamin D
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Summary:Due to the presence of receptors in the cells of numerous body tissues, vitamin D is associated with several physiological functions that go beyond calcium and phosphorus homoeostasis and control of bone metabolism in the body. In humans, several studies have associated lower vitamin D concentrations with numerous diseases, such as cancer, heart disease, autoimmune diseases and infectious diseases, and also with an increase in the total mortality rate of the population. Recently, this nutrient started to gain importance in veterinary medicine, and several articles have shown a correlation between low vitamin D status and diseases unrelated to bone metabolism. The present review aims to highlight the recent publications that investigated this relationship, bringing the evidence that exists so far in dogs and cats.
ISSN:0931-2439
1439-0396
DOI:10.1111/jpn.13259