A computational fluid dynamics study pre- and post-fistula closure in a coronary artery fistula

This study numerically investigated the hemodynamics of a patient-specific coronary artery fistula (CAF) before and after the fistula closure. The results indicated that the dilated fistula result in inadequate perfusion to other healthy aortas. Disturbed blood flow, aberrant WSSs, local negative pr...

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Bibliographic Details
Published in:Computer methods in biomechanics and biomedical engineering 2020-01, Vol.23 (1), p.33-42
Main Authors: Cao, Haoyao, Qiu, Yue, Yuan, Ding, Yu, Jianqun, Li, Da, Jiang, Yi, Su, Li, Peng, Liqing, Zheng, Tinghui
Format: Article
Language:English
Subjects:
Adult
Blood flow
Computational fluid dynamics
Computer applications
Coronary artery
Coronary Artery Disease - physiopathology
Coronary artery fistula
Coronary vessels
Coronary Vessels - physiopathology
Diastole - physiology
Fistula
Fistula - physiopathology
Fistulae
Fluid dynamics
Hemodynamics
Hemorheology
Humans
Hydrodynamics
Imaging, Three-Dimensional
Male
Models, Cardiovascular
Perfusion
Pressure
Pressure gradients
Stress, Mechanical
Systole - physiology
Thromboembolism
Thrombosis
wall shear stress
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Summary:This study numerically investigated the hemodynamics of a patient-specific coronary artery fistula (CAF) before and after the fistula closure. The results indicated that the dilated fistula result in inadequate perfusion to other healthy aortas. Disturbed blood flow, aberrant WSSs, local negative pressure gradients and sharp pressure changes are shown in both untreated and occluded fistula. Furthermore, extreme high WSS appeared at the fistula bending after the terminal closure. It was concluded that the fistula closure may effectively improve the phenomenon of stealing blood but worsen the unfavorable hemodyanmics predisposing the thrombosis formation due to its geometrical torturosity.
ISSN:1025-5842
1476-8259
DOI:10.1080/10255842.2019.1699540