Catechol-thiol-based dental adhesive inspired by underwater mussel adhesion

The critical problem associated with the underwater mussel adhesive catechol-based 3,4-dihydroxy-L-phenylalanine (DOPA) is its sensitivity to oxidation. To overcome this problem, mussels underwent etching in the presence of acidic pH conditions (

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Bibliographic Details
Published in:Acta biomaterialia 2020-02, Vol.103, p.92-101
Main Authors: Lee, Dohoon, Bae, Hyogeun, Ahn, Jinsoo, Kang, Taegon, Seo, Deog-Gyu, Hwang, Dong Soo
Format: Article
Language:English
Subjects:
Adhesion
Adhesive bonding
Adhesiveness
Adhesives
Animals
Bivalvia - physiology
Bonding strength
Catechol
Catechol, 3,4-Dihydroxy-l-phenylalanine (DOPA)
Catechols - pharmacology
Cell Survival - drug effects
Cross-Linking Reagents - chemistry
Dental adhesive
Dentin
Dentin-Bonding Agents - pharmacology
Dentistry
Dihydroxyphenylalanine
Etching
Fibroblasts - drug effects
Humans
Iron - chemistry
Magnetic Resonance Spectroscopy
Materials Testing
Mollusks
Mussels
Organic chemistry
Oxidation
Phenylalanine
Phosphoric acid
Resin Cements - pharmacology
Self-healing
Sulfhydryl Compounds - pharmacology
Underwater
Zirconia
Zirconium - chemistry
Zirconium dioxide
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Description
Summary:The critical problem associated with the underwater mussel adhesive catechol-based 3,4-dihydroxy-L-phenylalanine (DOPA) is its sensitivity to oxidation. To overcome this problem, mussels underwent etching in the presence of acidic pH conditions (
ISSN:1742-7061
1878-7568
DOI:10.1016/j.actbio.2019.12.002