Effect of tooth loss and nutritional status on outcomes after ischemic stroke

• Published in: Nutrition (Burbank, Los Angeles County, Calif.) Los Angeles County, Calif.), 2020-03, Vol.71, p.110606-110606, Article 110606
• Main Authors: Shiga, Yuji, Nezu, Tomohisa, Hosomi, Naohisa, Aoki, Shiro, Nishi, Hiromi, Naito, Hiroyuki, Kinoshita, Naoto, Ueno, Hiroki, Maruyama, Hirofumi
• Format: Article
• Language: English
• Subjects: Acute Disease; Aged; Alcohol use; Body mass index; Cardiac arrhythmia; Cardiovascular diseases; Cholesterol; Confidence intervals; Controlling Nutritional Status (CONUT) score; Diabetes; Evaluation; Female; Health risks; Heart Disease Risk Factors; Humans; Hypertension; Ischemia; Ischemic stroke; Ischemic Stroke - complications; Ischemic Stroke - physiopathology; Logistic Models; Male; Malnutrition; Malnutrition - complications; Malnutrition - physiopathology; Multivariate Analysis; Nutrition; Nutrition Assessment; Nutritional Status; Oral hygiene; Poor outcome; Prognosis; Regression analysis; Retrospective Studies; Severity of Illness Index; Statistical analysis; Stroke; Teeth; Tooth loss; Tooth Loss - complications; Tooth Loss - physiopathology
• ISSN: 0899-9007; 1873-1244
• DOI: 10.1016/j.nut.2019.110606

Tooth loss, closely associated with malnutrition, increases the risk for cardiovascular disease. The aim of this study was to examine the link between tooth loss, nutritional status, and stroke outcomes. We retrospectively analyzed 195 consecutive patients with acute ischemic stroke who were evaluated for tooth loss. Tooth loss was classified as mild or severe. Nutritional status was evaluated using the Controlling Nutritional Status (CONUT) score. A poor neurologic outcome was defined as a score of 3 to 6 on the modified Rankin Scale at 3 mo post-stroke onset; a score of 0 to 2 was defined as a good outcome. A significant correlation was observed between tooth loss and the CONUT score at admission (ρ = 0.156; P = 0.034). Patients with poor outcomes had higher CONUT scores (P < 0.001) and a greater frequency of severe tooth loss (P = 0.025). On multivariate analysis, severe tooth loss (odds ratio [OR], 3.93; 95% confidence interval [CI], 1.31–11.8) and the CONUT score (OR, 1.33; 95% CI, 1.02–1.74) were independently associated with poor stroke outcomes. Nutritional status was associated with tooth loss among patients with acute ischemic stroke. Severe tooth loss and a higher CONUT score were independently associated with poor stroke outcomes. •This study evaluated the link between tooth loss, nutritional status, and ischemic stroke outcome.•Severe tooth loss was independently associated with poor outcomes.•A higher Controlling Nutritional Status score was independently associated with poor outcomes.