Early left atrial dysfunction is associated with suboptimal cardiovascular health

• Published in: Echocardiography (Mount Kisco, N.Y.) N.Y.), 2020-01, Vol.37 (1), p.47-54
• Main Authors: Ocaranza, María Paz, Bambs, Claudia, Salinas, Manuel, Matamala, Cristian, Garcia, Lorena, Troncoso, Rodrigo, Pedrozo, Zully, Huidobro, Andrea, Venegas, Pia, Paredes, Fabio, Giacaman, Arturo, Zalaquett, Ricardo, Chiong, Mario, Verdejo, Hugo E., Ferreccio, Catterina, Lavandero, Sergio, Castro, Pablo F., Gabrielli, Luigi
• Format: Article
• Language: English
• Subjects: cardiovascular diseases; left atrium; strain
• ISSN: 0742-2822; 1540-8175
• DOI: 10.1111/echo.14568

Aims Two‐dimensional speckle‐tracking echocardiography can assess left atrial (LA) function by measuring atrial volumes and deformation parameters (strain, strain rate). This cross‐sectional analysis explores the association between ideal CV health (CVH), LA function, and systemic biomarkers in healthy individuals from the Chilean MAUCO Cohort. Methods We enrolled 95 MAUCO participants with different levels of CVH (mean age: 51 ± 8 years). We categorized participants into low or high CVH groups: A: 0‐2, or B: 3‐6 CVH risk factors. 2D echocardiography, glucose, insulin, total cholesterol, triglycerides, proBNP, hsCRP, insulin resistance index (HOMA), and right and left atrial strain (RASs and LASs, respectively) were determined. Results LASs was lower in Group A, while systolic and diastolic blood pressure (BP), body mass index (BMI), insulin, HOMA, total cholesterol, triglycerides, and LV and RV end‐diastolic volume were significantly higher in Group A than Group B (P