Genetic portrait of North-West Indian population based on X chromosome Alu insertion markers

In the present study, allele frequencies and forensic parameters of four ethnic groups (Brahmin, Khatri, Jat Sikh, and Scheduled Caste) of Punjab, India, at 10 Alu insertions of X chromosome were calculated. Six Alu markers were observed to be highly polymorphic with no significant deviations from H...

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Bibliographic Details
Published in:International journal of legal medicine 2020-09, Vol.134 (5), p.1655-1657
Main Authors: Singh, Gagandeep, Sandhu, Harkirat Singh, Srinivas, Yellapu, Matharoo, Kawaljit, Bhanwer, A. J. S.
Format: Article
Language:English
Subjects:
Alu Elements
Chromosomes
Chromosomes, Human, X - genetics
Ethnic Groups - genetics
Female
Forensic Medicine
Gene Frequency
Genetics, Population
Humans
India - ethnology
Male
Markers
Medical Law
Medicine
Medicine & Public Health
Minority & ethnic groups
Polymorphism, Genetic
Population Data
Population genetics
Populations
X chromosomes
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Summary:In the present study, allele frequencies and forensic parameters of four ethnic groups (Brahmin, Khatri, Jat Sikh, and Scheduled Caste) of Punjab, India, at 10 Alu insertions of X chromosome were calculated. Six Alu markers were observed to be highly polymorphic with no significant deviations from Hardy–Weinberg equilibrium and no linkage disequilibrium present in any marker. Multidimensional plot showed higher genetic affinity of studied populations with Asian populations. Overall, the tested markers were reliable and were found suitable in human forensics and population genetic studies.
ISSN:0937-9827
1437-1596
DOI:10.1007/s00414-019-02238-3