Role of strain imaging for assessment of myocardial viability in symptomatic myocardial infarction with single vessel disease: An observational study

Purpose To study and evaluate the predictive value of strain imaging parameters in patients undergoing viability assessment postmyocardial infarction (MI) in comparison with Dobutamine stress echocardiography (DSE) alone. Methods This was a prospective observational study (October, 2016–March, 2018)...

Full description

Saved in:
Bibliographic Details
Published in:Echocardiography (Mount Kisco, N.Y.) N.Y.), 2020-01, Vol.37 (1), p.55-61
Main Authors: Bhutani, Mohit, Vatsa, Deepankar, Rahatekar, Parag, Verma, Deepak, Nath, Ranjit K., Pandit, Neeraj
Format: Article
Language:English
Subjects:
dobutamine stress echocardiography
myocardial viability
strain imaging
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c3297-4841fabfd31e245edc12b7a917c2145ec51f9fc6443cbf2c6ecf819d0305bd833
cites cdi_FETCH-LOGICAL-c3297-4841fabfd31e245edc12b7a917c2145ec51f9fc6443cbf2c6ecf819d0305bd833
container_end_page 61
container_issue 1
container_start_page 55
container_title Echocardiography (Mount Kisco, N.Y.)
container_volume 37
creator Bhutani, Mohit
Vatsa, Deepankar
Rahatekar, Parag
Verma, Deepak
Nath, Ranjit K.
Pandit, Neeraj
description Purpose To study and evaluate the predictive value of strain imaging parameters in patients undergoing viability assessment postmyocardial infarction (MI) in comparison with Dobutamine stress echocardiography (DSE) alone. Methods This was a prospective observational study (October, 2016–March, 2018), which recruited 100 symptomatic patients with MI, and angiographically proven single vessel disease, LV dysfunction with severe hypokinesia/akinesia on 2D echocardiography and viability proven by baseline DSE. Patients undergoing primary PCI were excluded. Patients were recruited in two groups: DSE alone (first group) and strain imaging with DSE (second group). Revascularization was done in all patients. Patients were assessed at 3 months for functional recovery by 2D echocardiography. Results On 3 month follow‐up after revascularization, 37 patients (74%) in first group and 33 patients (66.67%) in second group had functional recovery. Dobutamine‐stimulated strain parameters such as circumferential strain (CS; P = .005), radial velocity (RV; P 
doi_str_mv 10.1111/echo.14567
format article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_2330059519</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2330059519</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3297-4841fabfd31e245edc12b7a917c2145ec51f9fc6443cbf2c6ecf819d0305bd833</originalsourceid><addsrcrecordid>eNp9kU1v1DAQhi0Eokvhwg9APiKkFI8_Ngm3atVSpEqVUHuOHGfcGiXx4vFulR_C_8XbLYgTc5nLM89I78vYexBnUOYzuod4Btqs6xdsBUaLqoHavGQrUWtZyUbKE_aG6IcQogbQr9mJgmbdtEas2K_vcUQePaecbJh5mOx9mO-5j4lbIiSacM4HYFqis2kIduT7YPswhrzwckHLtM1xsjm4f5kwe5tcDnHmjyE_cCrW8mlfjDjyIRBawi_8fOaxJ0x7e0DLHeXdsLxlr7wdCd8971N2d3lxu7mqrm--ftucX1dOybaudKPB294PClBqg4MD2de2hdrJkgc6A771bq21cr2Xbo3ON9AOQgnTD41Sp-zj0btN8ecOKXdTIIfjaGeMO-qkUkKY1kBb0E9H1KVIlNB321TCSksHojvU0B1q6J5qKPCHZ--un3D4i_7JvQBwBB7DiMt_VN3F5urmKP0NjIKW2A</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2330059519</pqid></control><display><type>article</type><title>Role of strain imaging for assessment of myocardial viability in symptomatic myocardial infarction with single vessel disease: An observational study</title><source>Wiley-Blackwell Read &amp; Publish Collection</source><creator>Bhutani, Mohit ; Vatsa, Deepankar ; Rahatekar, Parag ; Verma, Deepak ; Nath, Ranjit K. ; Pandit, Neeraj</creator><creatorcontrib>Bhutani, Mohit ; Vatsa, Deepankar ; Rahatekar, Parag ; Verma, Deepak ; Nath, Ranjit K. ; Pandit, Neeraj</creatorcontrib><description>Purpose To study and evaluate the predictive value of strain imaging parameters in patients undergoing viability assessment postmyocardial infarction (MI) in comparison with Dobutamine stress echocardiography (DSE) alone. Methods This was a prospective observational study (October, 2016–March, 2018), which recruited 100 symptomatic patients with MI, and angiographically proven single vessel disease, LV dysfunction with severe hypokinesia/akinesia on 2D echocardiography and viability proven by baseline DSE. Patients undergoing primary PCI were excluded. Patients were recruited in two groups: DSE alone (first group) and strain imaging with DSE (second group). Revascularization was done in all patients. Patients were assessed at 3 months for functional recovery by 2D echocardiography. Results On 3 month follow‐up after revascularization, 37 patients (74%) in first group and 33 patients (66.67%) in second group had functional recovery. Dobutamine‐stimulated strain parameters such as circumferential strain (CS; P = .005), radial velocity (RV; P &lt; .001), longitudinal strain (LS; P &lt; .001), and longitudinal strain rate (LSR; P &lt; .001) were found to be a significant predictor of viability. The greatest area under the curve (AUC) for the ROC curves was obtained for low dose dobutamine RV (AUC = 0.92), low dose dobutamine LS (AUC = 0.94), and low dose dobutamine LSR (AUC = 0.88). Positive predictive value of the combination of low dose DSE with strain parameters (RV‐97.2%, LS‐97.4%, and LSR‐87.5%) for myocardial viability was significantly higher than low dose DSE positive/low dose strain parameters negative patients as well as low dose DSE group alone. Conclusion Evaluation of strain parameters with low dose DSE is clinically feasible for the detection of myocardial viability and adds incremental value to the subjective and semiquantitative wall‐motion scoring. LS at low dose DSE with WMSI was found to have the highest positive predictive value.</description><identifier>ISSN: 0742-2822</identifier><identifier>EISSN: 1540-8175</identifier><identifier>DOI: 10.1111/echo.14567</identifier><identifier>PMID: 31868950</identifier><language>eng</language><publisher>United States</publisher><subject>dobutamine stress echocardiography ; myocardial viability ; strain imaging</subject><ispartof>Echocardiography (Mount Kisco, N.Y.), 2020-01, Vol.37 (1), p.55-61</ispartof><rights>2019 Wiley Periodicals, Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3297-4841fabfd31e245edc12b7a917c2145ec51f9fc6443cbf2c6ecf819d0305bd833</citedby><cites>FETCH-LOGICAL-c3297-4841fabfd31e245edc12b7a917c2145ec51f9fc6443cbf2c6ecf819d0305bd833</cites><orcidid>0000-0002-8258-0445</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/31868950$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Bhutani, Mohit</creatorcontrib><creatorcontrib>Vatsa, Deepankar</creatorcontrib><creatorcontrib>Rahatekar, Parag</creatorcontrib><creatorcontrib>Verma, Deepak</creatorcontrib><creatorcontrib>Nath, Ranjit K.</creatorcontrib><creatorcontrib>Pandit, Neeraj</creatorcontrib><title>Role of strain imaging for assessment of myocardial viability in symptomatic myocardial infarction with single vessel disease: An observational study</title><title>Echocardiography (Mount Kisco, N.Y.)</title><addtitle>Echocardiography</addtitle><description>Purpose To study and evaluate the predictive value of strain imaging parameters in patients undergoing viability assessment postmyocardial infarction (MI) in comparison with Dobutamine stress echocardiography (DSE) alone. Methods This was a prospective observational study (October, 2016–March, 2018), which recruited 100 symptomatic patients with MI, and angiographically proven single vessel disease, LV dysfunction with severe hypokinesia/akinesia on 2D echocardiography and viability proven by baseline DSE. Patients undergoing primary PCI were excluded. Patients were recruited in two groups: DSE alone (first group) and strain imaging with DSE (second group). Revascularization was done in all patients. Patients were assessed at 3 months for functional recovery by 2D echocardiography. Results On 3 month follow‐up after revascularization, 37 patients (74%) in first group and 33 patients (66.67%) in second group had functional recovery. Dobutamine‐stimulated strain parameters such as circumferential strain (CS; P = .005), radial velocity (RV; P &lt; .001), longitudinal strain (LS; P &lt; .001), and longitudinal strain rate (LSR; P &lt; .001) were found to be a significant predictor of viability. The greatest area under the curve (AUC) for the ROC curves was obtained for low dose dobutamine RV (AUC = 0.92), low dose dobutamine LS (AUC = 0.94), and low dose dobutamine LSR (AUC = 0.88). Positive predictive value of the combination of low dose DSE with strain parameters (RV‐97.2%, LS‐97.4%, and LSR‐87.5%) for myocardial viability was significantly higher than low dose DSE positive/low dose strain parameters negative patients as well as low dose DSE group alone. Conclusion Evaluation of strain parameters with low dose DSE is clinically feasible for the detection of myocardial viability and adds incremental value to the subjective and semiquantitative wall‐motion scoring. LS at low dose DSE with WMSI was found to have the highest positive predictive value.</description><subject>dobutamine stress echocardiography</subject><subject>myocardial viability</subject><subject>strain imaging</subject><issn>0742-2822</issn><issn>1540-8175</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2020</creationdate><recordtype>article</recordtype><recordid>eNp9kU1v1DAQhi0Eokvhwg9APiKkFI8_Ngm3atVSpEqVUHuOHGfcGiXx4vFulR_C_8XbLYgTc5nLM89I78vYexBnUOYzuod4Btqs6xdsBUaLqoHavGQrUWtZyUbKE_aG6IcQogbQr9mJgmbdtEas2K_vcUQePaecbJh5mOx9mO-5j4lbIiSacM4HYFqis2kIduT7YPswhrzwckHLtM1xsjm4f5kwe5tcDnHmjyE_cCrW8mlfjDjyIRBawi_8fOaxJ0x7e0DLHeXdsLxlr7wdCd8971N2d3lxu7mqrm--ftucX1dOybaudKPB294PClBqg4MD2de2hdrJkgc6A771bq21cr2Xbo3ON9AOQgnTD41Sp-zj0btN8ecOKXdTIIfjaGeMO-qkUkKY1kBb0E9H1KVIlNB321TCSksHojvU0B1q6J5qKPCHZ--un3D4i_7JvQBwBB7DiMt_VN3F5urmKP0NjIKW2A</recordid><startdate>202001</startdate><enddate>202001</enddate><creator>Bhutani, Mohit</creator><creator>Vatsa, Deepankar</creator><creator>Rahatekar, Parag</creator><creator>Verma, Deepak</creator><creator>Nath, Ranjit K.</creator><creator>Pandit, Neeraj</creator><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-8258-0445</orcidid></search><sort><creationdate>202001</creationdate><title>Role of strain imaging for assessment of myocardial viability in symptomatic myocardial infarction with single vessel disease: An observational study</title><author>Bhutani, Mohit ; Vatsa, Deepankar ; Rahatekar, Parag ; Verma, Deepak ; Nath, Ranjit K. ; Pandit, Neeraj</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3297-4841fabfd31e245edc12b7a917c2145ec51f9fc6443cbf2c6ecf819d0305bd833</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2020</creationdate><topic>dobutamine stress echocardiography</topic><topic>myocardial viability</topic><topic>strain imaging</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Bhutani, Mohit</creatorcontrib><creatorcontrib>Vatsa, Deepankar</creatorcontrib><creatorcontrib>Rahatekar, Parag</creatorcontrib><creatorcontrib>Verma, Deepak</creatorcontrib><creatorcontrib>Nath, Ranjit K.</creatorcontrib><creatorcontrib>Pandit, Neeraj</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Echocardiography (Mount Kisco, N.Y.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Bhutani, Mohit</au><au>Vatsa, Deepankar</au><au>Rahatekar, Parag</au><au>Verma, Deepak</au><au>Nath, Ranjit K.</au><au>Pandit, Neeraj</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Role of strain imaging for assessment of myocardial viability in symptomatic myocardial infarction with single vessel disease: An observational study</atitle><jtitle>Echocardiography (Mount Kisco, N.Y.)</jtitle><addtitle>Echocardiography</addtitle><date>2020-01</date><risdate>2020</risdate><volume>37</volume><issue>1</issue><spage>55</spage><epage>61</epage><pages>55-61</pages><issn>0742-2822</issn><eissn>1540-8175</eissn><abstract>Purpose To study and evaluate the predictive value of strain imaging parameters in patients undergoing viability assessment postmyocardial infarction (MI) in comparison with Dobutamine stress echocardiography (DSE) alone. Methods This was a prospective observational study (October, 2016–March, 2018), which recruited 100 symptomatic patients with MI, and angiographically proven single vessel disease, LV dysfunction with severe hypokinesia/akinesia on 2D echocardiography and viability proven by baseline DSE. Patients undergoing primary PCI were excluded. Patients were recruited in two groups: DSE alone (first group) and strain imaging with DSE (second group). Revascularization was done in all patients. Patients were assessed at 3 months for functional recovery by 2D echocardiography. Results On 3 month follow‐up after revascularization, 37 patients (74%) in first group and 33 patients (66.67%) in second group had functional recovery. Dobutamine‐stimulated strain parameters such as circumferential strain (CS; P = .005), radial velocity (RV; P &lt; .001), longitudinal strain (LS; P &lt; .001), and longitudinal strain rate (LSR; P &lt; .001) were found to be a significant predictor of viability. The greatest area under the curve (AUC) for the ROC curves was obtained for low dose dobutamine RV (AUC = 0.92), low dose dobutamine LS (AUC = 0.94), and low dose dobutamine LSR (AUC = 0.88). Positive predictive value of the combination of low dose DSE with strain parameters (RV‐97.2%, LS‐97.4%, and LSR‐87.5%) for myocardial viability was significantly higher than low dose DSE positive/low dose strain parameters negative patients as well as low dose DSE group alone. Conclusion Evaluation of strain parameters with low dose DSE is clinically feasible for the detection of myocardial viability and adds incremental value to the subjective and semiquantitative wall‐motion scoring. LS at low dose DSE with WMSI was found to have the highest positive predictive value.</abstract><cop>United States</cop><pmid>31868950</pmid><doi>10.1111/echo.14567</doi><tpages>7</tpages><orcidid>https://orcid.org/0000-0002-8258-0445</orcidid></addata></record>
fulltext fulltext
identifier ISSN: 0742-2822
ispartof Echocardiography (Mount Kisco, N.Y.), 2020-01, Vol.37 (1), p.55-61
issn 0742-2822
1540-8175
language eng
recordid cdi_proquest_miscellaneous_2330059519
source Wiley-Blackwell Read & Publish Collection
subjects dobutamine stress echocardiography
myocardial viability
strain imaging
title Role of strain imaging for assessment of myocardial viability in symptomatic myocardial infarction with single vessel disease: An observational study
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-21T07%3A26%3A19IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Role%20of%20strain%20imaging%20for%20assessment%20of%20myocardial%20viability%20in%20symptomatic%20myocardial%20infarction%20with%20single%20vessel%20disease:%20An%20observational%20study&rft.jtitle=Echocardiography%20(Mount%20Kisco,%20N.Y.)&rft.au=Bhutani,%20Mohit&rft.date=2020-01&rft.volume=37&rft.issue=1&rft.spage=55&rft.epage=61&rft.pages=55-61&rft.issn=0742-2822&rft.eissn=1540-8175&rft_id=info:doi/10.1111/echo.14567&rft_dat=%3Cproquest_cross%3E2330059519%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c3297-4841fabfd31e245edc12b7a917c2145ec51f9fc6443cbf2c6ecf819d0305bd833%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=2330059519&rft_id=info:pmid/31868950&rfr_iscdi=true