Pineal glioblastoma: Case report and literature review of an exceedingly rare etiology for pineal region mass

Pineal glioblastoma is an exceedingly rare potential etiology for a pineal region mass. The presentation, imaging appearance, and changes in treatment have been documented in a select number of cases since its first description in 1954. Through these cases, changes in treatment have shown to improve...

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Bibliographic Details
Published in:Clinical imaging 2020-03, Vol.60 (1), p.95-99
Main Authors: Sajan, Abin, Hewitt, Kevin, Soleiman, Aron, Velayudhan, Vinodkumar
Format: Article
Language:English
Subjects:
Biopsy
Brain cancer
Case reports
Chemotherapy
Endocrine system
Endoscopy
Etiology
Glioblastoma
Literature reviews
Medical imaging
Medical prognosis
Mutation
Neuroradiology
Pain
Patients
Pineal
Pineal gland
Radiation
Radiation therapy
Survival
Tumors
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Summary:Pineal glioblastoma is an exceedingly rare potential etiology for a pineal region mass. The presentation, imaging appearance, and changes in treatment have been documented in a select number of cases since its first description in 1954. Through these cases, changes in treatment have shown to improve outcomes in select patients, some of which have had survival times over two or three years. We present a case of a 39 year old female with biopsy proven pineal glioblastoma who demonstrates improvement on imaging and survival >12 months after treatment with radiation therapy and chemotherapy. Our case and the prior reported cases enable future research into improving treatment, classification, and imaging recognition for this unlikely disease. •Pineal glioblastoma is a rare, but important consideration for a pineal region mass.•The limited reported cases provide imaging findings and presentation information.•Outcomes have subjectively improved as treatment shifts to chemotherapy and radiation.•Our case and review of prior cases serve as guides for future diagnosis and treatment.
ISSN:0899-7071
1873-4499
DOI:10.1016/j.clinimag.2019.12.002