Prospective evAluatIon foR inhalation devices in Greek patients with COPD and asthma: The PAIR study

• Published in: Pulmonary pharmacology & therapeutics 2020-02, Vol.60, p.101882-101882, Article 101882
• Main Authors: Karampitsakos, Theodoros, Hillas, Georgios, Zervas, Eleftherios, Bakakos, Petros, Stratakos, Grigorios, Dimakou, Katerina, Manali, Efrosyni, Bouros, Demosthenes, Papiris, Spyridon, Tzouvelekis, Argyrios, Adamidis, Vasilios, Adamou, Helen, Agelidis, Xenophon, Albantakis, Konstantinos, Anaplioti, Aikaterini, Babalis, Christos, Balasoulis, George, Christou, Konstantinos, Filippidou, Christina, Fothiantakis, Emmanuel, Gavriilidou, Anna, Goulia, Hypakoe, Houliara, Konstantina, Kainis, Elias, Kakavelas, Paschalis, Kalampoka, Dionysia, Kalfountzos, George, Kammenidis, Savvas, Karkanis, Konstantinos, Karyanou, Eugenia, Katertzi, Maria, Kopanakis, Antonios, Kotantoula, Georgia, Liapikou, Adamantia, Manolakoglou, Nikolaos, Marosis, Konstantinos, Michailidou, Demetrios, Oikonomides, Peter, Palamidas, Anastasios, Papandreou, Athanasios, Pataka, Athanasia, Pitenis, Athanasios, Porpodis, Konstantinos, Stratis, Andreas, Terovitou, Chrysavgi, Trikrika, Evangelia, Tsiaga, Pashalia, Tsiounta, Theodora, Vlachou, Athina, Zois, Dimitrios
• Format: Article
• Language: English
• Subjects: Adherence; Administration, Inhalation; Adult; Aged; Aged, 80 and over; Anti-Asthmatic Agents - administration & dosage; Asthma; Asthma - drug therapy; Chronic obstructive pulmonary disease; Drug Delivery Systems - instrumentation; Dry Powder Inhalers - instrumentation; Dry Powder Inhalers - statistics & numerical data; Equipment Design; Female; Greece; Humans; Lung - drug effects; Male; Middle Aged; Patient Satisfaction; Prospective Studies; Pulmonary Disease, Chronic Obstructive - drug therapy; Questionnaire; Satisfaction; Surveys and Questionnaires; Test-retest reliability
• ISSN: 1094-5539; 1522-9629
• DOI: 10.1016/j.pupt.2019.101882

Chronic obstructive pulmonary disease (COPD) and asthma remain a major health burden. Adherence to inhaled therapy is critical in order to optimize treatment effectiveness. Properly designed questionnaires can assess patients’ satisfaction with their inhaler devices. A total of 766 patients with COPD, asthma or Asthma-COPD Overlap (ACO) were initially enrolled. During their first visit, patients were classified into three groups (Diskus™, Elpenhaler®, Turbuhaler®). Patients completed the FSI-10 questionnaire on Day 0 and Day 60. Test-retest reliability was evaluated. A total of 705 patients completed the study. FSI-10 questionnaire had good test-retest reliability (Total Intraclass Correlation Coefficient: 0.86). All dry powder inhaler (DPIs) yielded satisfactory results. Median score of FSI-10 questionnaire in first visit (FSI-10-I) was significantly higher for patients receiving Elpenhaler® (45, 95% CI: 44 to 46) than patients receiving Diskus™ (42, 95% CI: 41 to 43) and Turbuhaler® (42, 95% CI: 41 to 43) (p