Outcomes of Impella CP insertion during cardiac arrest: A single center experience

• Published in: Resuscitation 2020-02, Vol.147, p.53-56
• Main Authors: Kamran, Hayaan, Batra, Supria, Venesy, David M, Patten, Richard D, Waxman, Sergio, Pyne, Chris, Shah, Sachin P.
• Format: Article
• Language: English
• Subjects: Cardiac arrest; Cardiopulmonary resuscitation; Extracorporeal life support; Extracorporeal membrane oxygenation; Impella-CP; In-hospital mortality; Percutaneous mechanical circulatory support device
• ISSN: 0300-9572; 1873-1570
• DOI: 10.1016/j.resuscitation.2019.12.014

We sought to determine the outcomes of patients with an Impella CP percutaneous mechanical circulatory support (MCS) device deployed during a cardiac arrest. The Impella CP device is indicated for left ventricular support in patients with cardiogenic shock. The utility of percutaneous MCS in the setting of cardiac arrest during cardiopulmonary resuscitation (CPR) remains unclear. We retrospectively examined data from patients supported with an Impella CP device for cardiogenic shock complicated by cardiac arrest between April 2015 and April 2017 at a single academic medical center. Patients with cardiac arrest who underwent Impella CP placement during CPR were compared to those who had return of spontaneous circulation (ROSC) prior to Impella CP placement. We identified 22 patients with cardiogenic shock complicated by cardiac arrest (average age 64 years, 23% female) who underwent placement of an Impella CP device. The majority of patients (68%) underwent support for cardiogenic shock secondary to an acute myocardial infarction. Seven of the 22 patients (32%) underwent Impella CP placement during CPR and 15 (68%) underwent Impella CP insertion following ROSC. The in-hospital mortality was 86% in the group of patients who had the Impella CP placed during CPR and 56% in the group with ROSC prior to Impella CP insertion, (p = 0.19). Based on our single center retrospective analysis, the mortality rate of patients undergoing placement of an Impella CP during CPR is 86%. Further study is necessary to better understand the utility of the Impella CP mechanical circulatory support device during a cardiac arrest.