Twin studies of subjective sleep quality and sleep duration, and their behavioral correlates: Systematic review and meta-analysis of heritability estimates

•There was a moderate genetic influence on subjective sleep quality and sleep duration.•There was substantial heterogeneity across studies.•Heritability did not differ by geographical zone.•Age and sex were not significant moderators of the heritability of subjective sleep quality or sleep duration....

Full description

Saved in:
Bibliographic Details
Published in:Neuroscience and biobehavioral reviews 2020-02, Vol.109, p.78-89
Main Authors: Madrid-Valero, Juan J, Rubio-Aparicio, María, Gregory, Alice M., Sánchez-Meca, Julio, Ordoñana, Juan R.
Format: Article
Language:English
Subjects:
Genetic Phenomena - physiology
Heritability
Humans
Meta-Analysis
Sleep - physiology
Sleep duration
Sleep quality
Twin
Twin Studies as Topic - statistics & numerical data
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:•There was a moderate genetic influence on subjective sleep quality and sleep duration.•There was substantial heterogeneity across studies.•Heritability did not differ by geographical zone.•Age and sex were not significant moderators of the heritability of subjective sleep quality or sleep duration.•Genetic factors played a role in the associations between sleep variables and other factors. Twin studies have shown that a substantial proportion of the variance for sleep variables is due to genetic factors. However, there is still considerable heterogeneity among research reports. Our main objectives were to: 1) Review the twin literature regarding sleep quality and duration, as well as their behavioural correlates; 2) Estimate the mean heritability of subjective sleep quality and sleep duration; 3) Assess heterogeneity among studies on these topics; and 4) Search for moderator variables. Two parallel meta-analyses were carried out for sleep quality and sleep duration. Seventeen articles were included in the meta-analysis. Mean MZ correlations were consistently higher than DZ correlations. A mean heritability of 0.31 (95% CI: 0.20, 0.41) was found for subjective sleep quality (range: 0-0.43) and 0.38 (95% CI: 0.16, 0.56) for sleep duration (range: 0-1). Heterogeneity indexes were significant for both sleep quality (I2 = 98.77, p < .001) and sleep duration (I2 = 99.73, p < .001). The high heterogeneity warrants further research considering possible moderators that may affect heritability.
ISSN:0149-7634
1873-7528
DOI:10.1016/j.neubiorev.2019.12.028