Isolation of β-glucan from Eleusine coracana and its antibiofilm, antidiabetic, antioxidant, and biocompatible activities

Eleusine coracana (Finger millet) has high nutritional value with numerous health benefits and is of low cost. Isolation of beta-glucan (βG) from E. coracana (Ec-βG) has gained increasing research attention. UV–vis spectroscopy used to measure the surface plasmon resonance at 361 nm to confirm the p...

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Bibliographic Details
Published in:Microbial pathogenesis 2020-03, Vol.140, p.103955-103955, Article 103955
Main Authors: Divya, Mani, Karthikeyan, Sivashanmugam, Ravi, Cyril, Govindarajan, Marimuthu, Alharbi, Naiyf S., Kadaikunnan, Shine, Khaled, Jamal M., Almanaa, Taghreed N., Vaseeharan, Baskaralingam
Format: Article
Language:English
Subjects:
Antibacterial activity
Biomolecules
Finger millet
Hemolysis assay
Polysaccharides
β-Glucan
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Summary:Eleusine coracana (Finger millet) has high nutritional value with numerous health benefits and is of low cost. Isolation of beta-glucan (βG) from E. coracana (Ec-βG) has gained increasing research attention. UV–vis spectroscopy used to measure the surface plasmon resonance at 361 nm to confirm the presence of polysaccharides (glucan molecules) in Ec-βG. X-ray diffraction analysis of Ec-βG displayed a crystalline nature and confirmed the presence of the βG molecule. Further, the bioactive compounds of Ec-βG were screened using gas chromatography-mass spectrometry. The antibacterial activity of Ec-βG against both Gram-positive (Lysinibacillus fusiformis, Enterococcus faecalis) and Gram-negative (Proteus vulgaris, Shigella sonnei) bacteria were assessed through minimum inhibitory concentrations
ISSN:0882-4010
1096-1208
DOI:10.1016/j.micpath.2019.103955