A Randomized Controlled Trial of Three Noninvasive Analgesic Techniques for the Prevention of Pain During Facial Injections

Abstract Background Injections are associated with a certain amount of pain, the tolerance of which can vary between individuals. With regard to noninvasive pain control techniques in subcutaneous injections, few studies with adequate levels of evidence and design quality exist to support any specif...

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Bibliographic Details
Published in:Aesthetic surgery journal 2021-01, Vol.41 (1), p.74-79
Main Authors: Salmerón-González, Enrique, García-Vilariño, Elena, Sánchez-García, Alberto, Pérez-García, Alberto, Ruiz-Cases, Alberto, Valverde-Navarro, Alfonso
Format: Article
Language:English
Subjects:
Analgesics - therapeutic use
Anesthetics, Local
Double-Blind Method
Female
Humans
Male
Pain - drug therapy
Pain Management
Pain Measurement
Single-Blind Method
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Summary:Abstract Background Injections are associated with a certain amount of pain, the tolerance of which can vary between individuals. With regard to noninvasive pain control techniques in subcutaneous injections, few studies with adequate levels of evidence and design quality exist to support any specific analgesic method. Objectives In this study, we evaluated the efficacy of 3 noninvasive analgesic techniques (cold, anesthetic cream, and vibration) during subcutaneous forehead injections in 100 healthy volunteers. Methods This randomized, single-blind, controlled trial comprised 100 healthy volunteers. Every patient received 4 forehead injections of 0.1 mL physiological saline through 29G needles after 1 of 3 noninvasive analgesic techniques (cold, vibration, or anesthetic cream) or control treatment was applied to each injection site. The results were evaluated through a survey that included a visual analog scale for pain measurements. Results All analgesic methods demonstrated better pain control than the no-treatment arm (P 
ISSN:1090-820X
1527-330X
DOI:10.1093/asj/sjz380