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Prevalence of urogenital mycoplasmas in women with systemic lupus erythematosus (SLE): preliminary study

The aim of this study was to determine the occurrence of urogenital mycoplasmas in urogenital tract of women with systemic lupus erythematosus (SLE). The study group included 36 women diagnosed with SLE and 100 healthy controls. Mycoplasmas were detected with microculture and PCR in 13/36 (36.1%) wo...

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Published in:European journal of clinical microbiology & infectious diseases 2020-04, Vol.39 (4), p.717-721
Main Authors: Alicja, Ekiel, Małgorzata, Romanik, Małgorzata, Aptekorz, Elżbieta, Semik-Grabarczyk, Paweł, Cieślik, Dominika, Smolec, Jarosław, Jóźwiak, Michał, Holecki, Gayane, Martirosian
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Language:English
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Summary:The aim of this study was to determine the occurrence of urogenital mycoplasmas in urogenital tract of women with systemic lupus erythematosus (SLE). The study group included 36 women diagnosed with SLE and 100 healthy controls. Mycoplasmas were detected with microculture and PCR in 13/36 (36.1%) women with SLE and in 25/100 (25%) controls. In both groups, U. parvum occurred significantly more frequently. M. genitalium was detected in 3/36 (8.3%) SLE patients and in 3/100 (3%) controls. FVU as a material decreased the number of positive results from 33.3% to 30.6% compared with swabs. Although the incidence of mycoplasmas in urogenital tract of women with SLE and controls did not differ statistically, it is important to consider them as a potential etiology of urogenital infection when clinical symptoms are present, but etiology is unknown or uncertain.
ISSN:0934-9723
1435-4373
DOI:10.1007/s10096-019-03783-w