Surgical management of locally-advanced and metastatic hepatoblastoma

Advanced stage hepatoblastoma, including both locally advanced primary tumors as well as metastatic disease, poses unique clinical challenges. Despite substantial advances in chemotherapeutics, surgical extirpation remains the mainstay of cure for this tumor. Locally advanced tumors that involve mul...

Full description

Saved in:
Bibliographic Details
Published in:Seminars in pediatric surgery 2019-12, Vol.28 (6), p.150856-150856, Article 150856
Main Authors: Lake, Charissa M., Tiao, Gregory M., Bondoc, Alexander J.
Format: Article
Language:English
Subjects:
Extreme resection
Hepatoblastoma
Indocyanine green
Liver transplant
PRETEXT
Pulmonary metastasectomy
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Advanced stage hepatoblastoma, including both locally advanced primary tumors as well as metastatic disease, poses unique clinical challenges. Despite substantial advances in chemotherapeutics, surgical extirpation remains the mainstay of cure for this tumor. Locally advanced tumors that involve multiple hepatic lobes and/or invade significant vascular structures can be managed either by complex hepatic resections or liver transplantation. We review the indications, roles, and outcomes of these surgical approaches as well as those for the resection of pulmonary metastases.
ISSN:1055-8586
1532-9453
DOI:10.1016/j.sempedsurg.2019.150856