EFFECT OF IMPURITIES AND ASSOCIATED MINERALS ON QUARTZ TOXICITY

Pulmonary toxicity by inhalation of two coal-mine dusts containing 15 and 5% quartz was compared with that of artificial coal–quartz mixtures having the same quartz content. The natural dust mixtures were slightly toxic, while the artificial ones produced considerably more lesions and fibrosis in re...

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Published in:The Annals of occupational hygiene 1982, Vol.26 (5), p.625-634
Main Authors: LE BOUFFANT, L., DANIEL, H., MARTIN, J. C., BRUYÈRE, S.
Format: Article
Language:English
Subjects:
Animals
chemical reactions
coal
crystal impurities
dust
Dust - adverse effects
Dust - analysis
Female
mining
quartz
Quartz - adverse effects
Quartz - analysis
Rats
Rats, Inbred Strains
respiratory pathology
Silicon Dioxide - adverse effects
toxicity
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container_issue 5
container_start_page 625
container_title The Annals of occupational hygiene
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creator LE BOUFFANT, L.
DANIEL, H.
MARTIN, J. C.
BRUYÈRE, S.
description Pulmonary toxicity by inhalation of two coal-mine dusts containing 15 and 5% quartz was compared with that of artificial coal–quartz mixtures having the same quartz content. The natural dust mixtures were slightly toxic, while the artificial ones produced considerably more lesions and fibrosis in relation to the quartz content. Intratracheal tests carried out with sands of various origins show that certain types of quartz may be only slightly toxic at first, then they progressively gain the usual toxicity of quartz in the lungs. Quartz extracted from various coal-mine dusts by chemical attack was also very toxic. It is inferred that the absence of toxicity of coal-mine dust containing quartz is due to the presence of protective impurities on the surface of the quartz particles or to the inhibitory action of certain constituents.
doi_str_mv 10.1093/annhyg/26.5.625
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source Oxford University Press Archive
subjects Animals
chemical reactions
coal
crystal impurities
dust
Dust - adverse effects
Dust - analysis
Female
mining
quartz
Quartz - adverse effects
Quartz - analysis
Rats
Rats, Inbred Strains
respiratory pathology
Silicon Dioxide - adverse effects
toxicity
title EFFECT OF IMPURITIES AND ASSOCIATED MINERALS ON QUARTZ TOXICITY
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