A multicentre study of 244 pregnancies in undifferentiated connective tissue disease: maternal/fetal outcomes and disease evolution

Abstract Objectives To investigate fetal/perinatal and maternal outcomes from a large multicentre cohort of women diagnosed with UCTD. Methods This multicentre retrospective cohort study describes the outcomes of 224 pregnancies in 133 consecutive women with a diagnosis of UCTD, positive for ANA and...

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Published in:Rheumatology (Oxford, England) England), 2020-09, Vol.59 (9), p.2412-2418
Main Authors: Radin, Massimo, Schreiber, Karen, Cecchi, Irene, Bortoluzzi, Alessandra, Crisafulli, Francesca, de Freitas, Cristiano M, Bacco, Beatrice, Rubini, Elena, Foddai, Silvia G, Padovan, Melissa, Gallo Cassarino, Silvia, Franceschini, Franco, Andrade, Danieli, Benedetto, Chiara, Govoni, Marcello, Bertero, Tiziana, Marozio, Luca, Roccatello, Dario, Andreoli, Laura, Sciascia, Savino
Format: Article
Language:English
Subjects:
Abortion, Spontaneous - epidemiology
Abortion, Spontaneous - etiology
Adult
Antibodies, Antinuclear - blood
Antibodies, Antinuclear - immunology
Antibodies, Antiphospholipid - blood
Antibodies, Antiphospholipid - immunology
Autoantibodies - blood
Autoantibodies - immunology
Female
Fetal Growth Retardation - epidemiology
Fetal Growth Retardation - etiology
Humans
Live Birth - epidemiology
Pregnancy
Pregnancy Complications - blood
Pregnancy Complications - etiology
Pregnancy Complications - immunology
Pregnancy Outcome - epidemiology
Retrospective Studies
Stillbirth - epidemiology
Undifferentiated Connective Tissue Diseases - blood
Undifferentiated Connective Tissue Diseases - complications
Undifferentiated Connective Tissue Diseases - immunology
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Summary:Abstract Objectives To investigate fetal/perinatal and maternal outcomes from a large multicentre cohort of women diagnosed with UCTD. Methods This multicentre retrospective cohort study describes the outcomes of 224 pregnancies in 133 consecutive women with a diagnosis of UCTD, positive for ANA and aged
ISSN:1462-0324
1462-0332
DOI:10.1093/rheumatology/kez620