Ultrasound-assisted synthesis of heterocyclic compounds

In this review, we tried to underscore the synthesis of the heterocyclic compounds under assisted ultrasonic irradiation. The ultrasonic irradiation has been applied for medicinal chemistry and drug discovery process since it dramatically reduces reaction times, from days or hours to minutes. Also,...

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Bibliographic Details
Published in:Molecular diversity 2020-08, Vol.24 (3), p.771-820
Main Authors: Mohammadi Ziarani, Ghodsi, kheilkordi, Zohreh, Gholamzadeh, Parisa
Format: Article
Language:English
Subjects:
Biochemistry
Biomedical and Life Sciences
Chemistry Techniques, Synthetic - methods
Comprehensive Review
Heterocyclic Compounds - chemical synthesis
Heterocyclic Compounds - chemistry
Irradiation
Life Sciences
Organic Chemistry
Pharmacy
Polymer Sciences
Ultrasonic Waves
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Summary:In this review, we tried to underscore the synthesis of the heterocyclic compounds under assisted ultrasonic irradiation. The ultrasonic irradiation has been applied for medicinal chemistry and drug discovery process since it dramatically reduces reaction times, from days or hours to minutes. Also, ultrasonic irradiation provides lower cost, excellent yields, greater purity, and simple workups as compared to lower yields, longer reaction times, lesser purity and in the conventional methods. In this review, we have compared synthesis of the heterocyclic compounds under ultrasonic irradiation with other methods. Graphic abstract
ISSN:1381-1991
1573-501X
DOI:10.1007/s11030-019-09964-1