Risk factors for cow's milk protein allergy in infants: a multicenter survey

To investigate the risk factors for cow's milk protein allergy (CMPA) among infants through a multicenter clinical study. A total of 1 829 infants, aged 1-12 months, who attended the outpatient service of the pediatric department in six hospitals in Shenzhen, China from June 2016 to May 2017 we...

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Published in:Zhongguo dang dai er ke za zhi 2020-01, Vol.22 (1), p.42-46
Main Authors: Zhang, Ji-Yong, Zhou, Shao-Ming, Wang, Shao-Hua, Sui, Feng-Xuan, Gao, Wu-Hong, Liu, Qing, Cai, Hua-Bo, Jiang, Hong-Ying, Li, Wei-Yan, Wang, Li-Ting, Li, Li, Zhao, Wei, Ying, Jing, Wu, Qian-Zhen, Weng, Bi-Xia, Zeng, Yong-Mei
Format: Article
Language:Chinese
Subjects:
Animals
Cattle
China
Female
Humans
Infant
Milk Hypersensitivity
Milk Proteins
Pregnancy
Risk Factors
Surveys and Questionnaires
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Summary:To investigate the risk factors for cow's milk protein allergy (CMPA) among infants through a multicenter clinical study. A total of 1 829 infants, aged 1-12 months, who attended the outpatient service of the pediatric department in six hospitals in Shenzhen, China from June 2016 to May 2017 were enrolled as subjects. A questionnaire survey was performed to screen out suspected cases of CMPA. Food avoidance and oral food challenge tests were used to make a confirmed diagnosis of CMPA CMPA. A multivariate logistic regression analysis was used to investigate the risk factors for CMPA. Among the 1 829 infants, 82 (4.48%) were diagnosed with CMPA. The multivariate logistic regression analysis showed that maternal food allergy (OR=4.91, 95%CI: 2.24-10.76, P
ISSN:1008-8830
DOI:10.7499/j.issn.1008-8830.2020.01.009