Celiac disease and hematological abnormalities in children with recurrent aphthous stomatitis

Background Recurrent aphthous stomatitis (RAS) is one of the most common diseases of the oral mucosa and may be related to vitamin deficiencies or systemic diseases such as celiac disease (CD). The aim of this study was to investigate the frequency of hematinic deficiency and CD in children with RAS...

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Bibliographic Details
Published in:Pediatrics international 2020-06, Vol.62 (6), p.705-710
Main Authors: Yılmaz, Songül, Tuna Kırsaçlıoğlu, Ceyda, Şaylı, Tülin Revide
Format: Article
Language:English
Subjects:
Adolescent
Anemia
Anemia, Iron-Deficiency - epidemiology
Aphthous stomatitis
Celiac disease
Celiac Disease - blood
Celiac Disease - epidemiology
Child
Child, Preschool
Children
Erythrocyte Indices
Female
Ferritin
Ferritins - analysis
Folic acid
Folic Acid Deficiency - epidemiology
hematinic deficiency
Hematology
Hemoglobin
Hemoglobins - analysis
Humans
Infant
Iron
Iron deficiency
Male
Malnutrition
Medical records
Mucosa
Nutrient deficiency
Nutritional Status
Pediatrics
Stomatitis
Stomatitis, Aphthous - blood
Stomatitis, Aphthous - epidemiology
Turkey - epidemiology
Vitamin B 12 Deficiency - epidemiology
Vitamin B12
Vitamin deficiency
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Summary:Background Recurrent aphthous stomatitis (RAS) is one of the most common diseases of the oral mucosa and may be related to vitamin deficiencies or systemic diseases such as celiac disease (CD). The aim of this study was to investigate the frequency of hematinic deficiency and CD in children with RAS. Methods The medical records of patients diagnosed with RAS were reviewed for the presence of hematinic deficiencies (hemoglobin, mean corpuscular volume, ferritin, vitamin B12, folic acid), and CD. The study group included 108 children with RAS and 57 healthy children who were evaluated for hematological abnormalities in routine evaluation. Results The frequency of a family history of RAS was significantly higher in the RAS group compared to the control group (34.2% vs 7%, respectively; P 
ISSN:1328-8067
1442-200X
DOI:10.1111/ped.14155