Impact of Malnutrition on Outcomes in Patients Undergoing Transjugular Intrahepatic Portosystemic Shunt Insertion

Background Malnutrition is common in patients with cirrhosis and is associated with poor outcomes after hepatic resection and liver transplantation. Transjugular intrahepatic portosystemic shunt (TIPS) is performed for complications of cirrhosis. Aim To assess the impact of malnutrition on TIPS outc...

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Bibliographic Details
Published in:Digestive diseases and sciences 2020-11, Vol.65 (11), p.3332-3340
Main Authors: Chiang, Ryan S., Parish, Alice, Niedzwiecki, Donna, Kappus, Matthew R., Muir, Andrew J.
Format: Article
Language:English
Subjects:
Biochemistry
Female
Gastroenterology
Hepatology
Hospital Charges - statistics & numerical data
Humans
Length of Stay - statistics & numerical data
Liver Cirrhosis - complications
Male
Malnutrition - complications
Malnutrition - mortality
Medicine
Medicine & Public Health
Middle Aged
Oncology
Original Article
Portasystemic Shunt, Transjugular Intrahepatic
Retrospective Studies
Skilled Nursing Facilities - statistics & numerical data
Transplant Surgery
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Summary:Background Malnutrition is common in patients with cirrhosis and is associated with poor outcomes after hepatic resection and liver transplantation. Transjugular intrahepatic portosystemic shunt (TIPS) is performed for complications of cirrhosis. Aim To assess the impact of malnutrition on TIPS outcomes. Methods A retrospective analysis was performed using the Healthcare Cost and Utilization Project: National Inpatient Sample database for TIPS procedures from 2005 to 2014. The primary end point was in-hospital mortality. The association of specific malnutrition diagnostic codes and race–ethnicity on mortality was evaluated with survey-weighted logistic regression adjusted for age, gender, admission type, insurance payer, hospital region, comorbidities, and length of stay (LOS). Results From 2005 to 2014, an estimated 53,207 (95% CI 49,330–57,085) admissions with TIPS occurred. A diagnosis of malnutrition was present in 11%. In-hospital death post-TIPS occurred in 15.0% versus 10.7% ( p value 
ISSN:0163-2116
1573-2568
DOI:10.1007/s10620-019-06038-y