Anemia and iron deficiency in compensated and decompensated cirrhosis: Prevalence and impact on clinical outcomes

Background and Aim Iron deficiency anemia (IDA)is the leading cause of anemia worldwide. Data on prevalence and clinical impact of anemia in cirrhosis are scarce. Aim was to report on the following:(i) prevalence of anemia and IDA in cirrhosis and (ii) its possible impact on clinical outcomes. Metho...

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Bibliographic Details
Published in:Journal of gastroenterology and hepatology 2020-09, Vol.35 (9), p.1619-1627
Main Authors: Paternostro, Rafael, Kapzan, Lea, Mandorfer, Mattias, Schwarzer, Remy, Benedikt, Schaefer, Viveiros, André, Bauer, David, Ferlitsch, Monika, Zoller, Heinz, Trauner, Michael, Ferlitsch, Arnulf
Format: Article
Language:English
Subjects:
Anemia
Cirrhosis
Clinical outcomes
decompensation
Hemoglobin
Iron
Iron deficiency
iron‐deficiency anemia
Liver cirrhosis
Liver diseases
Mortality
Nutrient deficiency
portal hypertension
Risk factors
Transferrins
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Summary:Background and Aim Iron deficiency anemia (IDA)is the leading cause of anemia worldwide. Data on prevalence and clinical impact of anemia in cirrhosis are scarce. Aim was to report on the following:(i) prevalence of anemia and IDA in cirrhosis and (ii) its possible impact on clinical outcomes. Methods Consecutive cirrhotic patients from a prospective registry study were included. Anemia was defined as hemoglobin concentration ≤ 12 g/dL. IDA was defined as Hb ≤ 12 g/dL + transferrin‐saturation 
ISSN:0815-9319
1440-1746
DOI:10.1111/jgh.14988