Electrophysiological characteristics and clinical values of left bundle branch current of injury in left bundle branch pacing

Background Left bundle branch pacing (LBBP) is emerging as a novel option for physiological ventricular pacing. The impact of current of injury (COI) at left bundle branch (LBB) has not been previously evaluated. Methods Consecutive patients with QRS duration less than 120 milliseconds referred for...

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Bibliographic Details
Published in:Journal of cardiovascular electrophysiology 2020-04, Vol.31 (4), p.834-842
Main Authors: Su, Lan, Xu, Tiancheng, Cai, Mengxing, Xu, Lei, Vijayaraman, Pugazhendhi, Sharma, Parikshit S., Chen, Xiao, Zheng, Rujie, Wu, Shengjie, Huang, Weijian
Format: Article
Language:English
Subjects:
Action Potentials
Aged
Aged, 80 and over
Arrhythmias, Cardiac - diagnosis
Arrhythmias, Cardiac - physiopathology
Arrhythmias, Cardiac - therapy
Bundle of His - injuries
Bundle of His - physiopathology
capture threshold
Cardiac Pacing, Artificial - adverse effects
current of injury
Electrocardiography
Female
Heart Failure - diagnosis
Heart Failure - physiopathology
Heart Failure - therapy
Heart Injuries - diagnosis
Heart Injuries - etiology
Heart Injuries - physiopathology
Heart Rate
Humans
lead stability
left bundle branch pacing
left ventricular septal myocardial capture
Male
Middle Aged
Retrospective Studies
Time Factors
Treatment Outcome
Ventricle
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Summary:Background Left bundle branch pacing (LBBP) is emerging as a novel option for physiological ventricular pacing. The impact of current of injury (COI) at left bundle branch (LBB) has not been previously evaluated. Methods Consecutive patients with QRS duration less than 120 milliseconds referred for LBBP in whom LBB potentials were recorded were included from August 2018 to March 2019. We recorded LBB COI during LBBP and assessed its impact on the pacing parameters and complications during implantation and at short term follow‐up. Results A total of 115 patients with an identifiable LBB potential at implant were included. LBB COI was confirmed in 77 (67.0%) of these patients. Three types of LBB COI were observed. LBB was captured in all patients at a pacing threshold less than 1.5 V/0.5 ms in COI(+) patients, while present in only 29 patients without an LBB COI(−) (100% vs 76.3%; P 
ISSN:1045-3873
1540-8167
DOI:10.1111/jce.14377