Cholangiocarcinoma, 10-Year Survival After Liver Transplantation: A Case Report

Cholangiocarcinoma is the second most common neoplasm in the liver, with a very poor, short-term prognosis. Today, surgery associated with or without an adjuvant is the only curative treatment. Liver transplantation (LT) is the best treatment for hepatocellular carcinoma tumor. In recent years, trea...

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Bibliographic Details
Published in:Transplantation proceedings 2020-03, Vol.52 (2), p.592-593
Main Authors: Herrero Torres, Maria Angeles, Dominguez Bastante, Mireia, Molina Raya, Andrea, Palomo Lopez, Irina, Santoyo Villalba, Julio, Villegas Herrera, Maria Trinidad, Becerra Massare, Antonio, Brea Gomez, Esther, Zambudio Carroll, Natalia, Villar del Moral, Jesus Maria
Format: Article
Language:English
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Summary:Cholangiocarcinoma is the second most common neoplasm in the liver, with a very poor, short-term prognosis. Today, surgery associated with or without an adjuvant is the only curative treatment. Liver transplantation (LT) is the best treatment for hepatocellular carcinoma tumor. In recent years, treatment of hilar cholangiocarcinoma by LT associated with neoadjuvant therapy has been studied under a criterion. But could it be possible to apply LT like the curative treatment of intrahepatic cholangiocarcinoma (iCC)? Initially the answer is no, but there are different studies about incidental LT in patients with iCC that demonstrate survival over 40% to 50%. In our center, we conducted a review of 468 transplants completed between 2002 and 2018, and we identified 1 case of incidental LT in a patient with iCC with an overall survival of 10 years. Because there is currently an increase in donors owing to the expansion of the criteria, a study to consider extending the criteria of LT to include iCC would be beneficial. •Liver transplantation is a curative treatment for some selected tumors: hepatocellular carcinoma and hepatoblastoma.•Accidentally, patients with cholangiocarcinoma have been transplanted under other diagnosis like hepatocellular carcinoma.•In our center, we present 1 transplantation patient with a final result of cholangiocarcinoma in the hepatectomy specimen who is still alive after 10 years of follow-up.•Liver transplantation could be a new indication for intrahepatic cholangiocarcinoma in the future.
ISSN:0041-1345
1873-2623
DOI:10.1016/j.transproceed.2019.12.030