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A molecular recognition-activatable DNA nanofirecracker enables signal-enhanced imaging in living cells
We propose an aptamer-tethered DNA nanofirecracker probe that realizes molecular recognition-activatable disassembly of the DNA nanostructure for imaging of target molecules in living cells. The design principle offers a new paradigm to develop nucleic acid nanocircuits for live-cell study and manip...
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| Published in: | Chemical communications (Cambridge, England) England), 2020-03, Vol.56 (21), p.3131-3134 |
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| Main Authors: | , , , |
| Format: | Article |
| Language: | English |
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| cited_by | cdi_FETCH-LOGICAL-c363t-ec13abf996e0cd89fd2d1d2c943046f5465fbf89d07a94116ff08c257693ec6a3 |
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| cites | cdi_FETCH-LOGICAL-c363t-ec13abf996e0cd89fd2d1d2c943046f5465fbf89d07a94116ff08c257693ec6a3 |
| container_end_page | 3134 |
| container_issue | 21 |
| container_start_page | 3131 |
| container_title | Chemical communications (Cambridge, England) |
| container_volume | 56 |
| creator | Xing, Xiaojing Li, Jin Qiu, Liping Tan, Weihong |
| description | We propose an aptamer-tethered DNA nanofirecracker probe that realizes molecular recognition-activatable disassembly of the DNA nanostructure for imaging of target molecules in living cells. The design principle offers a new paradigm to develop nucleic acid nanocircuits for live-cell study and manipulation.
An aptamer-tethered DNA nanofirecracker probe that realizes molecular recognition-activatable disassembly of the DNA nanostructure for signal-enhanced bioimaging in living cells. |
| doi_str_mv | 10.1039/c9cc09682e |
| format | article |
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| identifier | ISSN: 1359-7345 |
| ispartof | Chemical communications (Cambridge, England), 2020-03, Vol.56 (21), p.3131-3134 |
| issn | 1359-7345 1364-548X |
| language | eng |
| recordid | cdi_proquest_miscellaneous_2355940339 |
| source | Royal Society of Chemistry:Jisc Collections:Royal Society of Chemistry Read and Publish 2022-2024 (reading list) |
| subjects | Aptamers, Nucleotide - chemistry Cells (biology) Deoxyribonucleic acid DNA DNA - chemistry Fluorescent Dyes - chemistry Humans MCF-7 Cells Nanostructures - chemistry Optical Imaging RNA, Messenger - analysis Target recognition |
| title | A molecular recognition-activatable DNA nanofirecracker enables signal-enhanced imaging in living cells |
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