Promising antiviral, antimicrobial and therapeutic properties of green nanoceria

To demonstrate synthesis of cerium oxide nanoparticles (CeO NPs) by a green method using , and investigate their therapeutic applications. Structural, vibrational and luminescent properties were established using x-ray diffraction, Fourier transformed infrared spectroscopy, Raman spectroscopy, ultra...

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Bibliographic Details
Published in:Nanomedicine (London, England) England), 2020-02, Vol.15 (5), p.467-488
Main Authors: Mohamed, Hamza E Ahmed, Afridi, Shakeeb, Khalil, Ali T, Ali, Muhammad, Zohra, Tanzeel, Akhtar, Ribqa, Ikram, Aamer, Shinwari, Zabta K, Maaza, Malik
Format: Article
Language:English
Subjects:
Alzheimer's disease
antibacterial
antifungal
Antimicrobial agents
antioxidant
antiviral
Antiviral drugs
Biocompatibility
biocompatible
Biosynthesis
cerium oxide
Kinases
Mortality
nanoparticles
Nanotechnology
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Summary:To demonstrate synthesis of cerium oxide nanoparticles (CeO NPs) by a green method using , and investigate their therapeutic applications. Structural, vibrational and luminescent properties were established using x-ray diffraction, Fourier transformed infrared spectroscopy, Raman spectroscopy, ultraviolet absorption spectroscopy, selected area electron diffraction, electron microscopy and photolumincence spectroscopy. Therapeutic properties were established using different assays. CeO NPs were determined to be crystalline in nature with a grain size of approximately 14 nm. They had characteristic Ce–O vibration at 481 cm . Photoluminescence spectra revealed broad bands at 463 and 600 nm. ζ potential was recorded as -17.2 mV. Potent antimicrobial and antiviral properties with hemocompatibility were reported. Biosynthesized CeO NPs revealed multifunctional therapeutic properties.
ISSN:1743-5889
1748-6963
DOI:10.2217/nnm-2019-0368