How could gold nanourchins be applied in the clinic?

[...]the electromagnetic field increases profoundly at the tips of AuNU spikes. [...]AuNUs are ideal for imaging that is based on SERS, two-photon photoluminescence, magnetic resonance (MR), positron emission tomography (PET), x-ray computed tomography, single-photon emission computed tomography (SP...

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Bibliographic Details
Published in:Nanomedicine (London, England) England), 2020-04, Vol.15 (9), p.829-832
Main Authors: Samhadaneh, Dana M, Chu, Siwei, Maysinger, Dusica, Stochaj, Ursula
Format: Article
Language:English
Subjects:
Ablation
Antibiotics
Biomarkers
cancer
Cancer therapies
Clinical trials
diagnostics
Disease
gold nanoparticles
gold nanourchins
Immunotherapy
Kinases
medical imaging
Nanomaterials
nanoparticle imaging
Nanoparticles
Pathogens
Quality control
R&D
Research & development
therapeutics
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Summary:[...]the electromagnetic field increases profoundly at the tips of AuNU spikes. [...]AuNUs are ideal for imaging that is based on SERS, two-photon photoluminescence, magnetic resonance (MR), positron emission tomography (PET), x-ray computed tomography, single-photon emission computed tomography (SPECT), ultrasound and optical imaging (7). Notably, sublethal AuNU effects are only beginning to emerge (33). [...]many aspects of AuNU-dependent bio-nano interactions remain to be characterized. Interestingly, AuNUs can be produced on wafers (4) or immobilized on adhesive tape (11). [...]future applications may take advantage of AuNUs that are immobilized on biocompatible support.
ISSN:1743-5889
1748-6963
DOI:10.2217/nnm-2019-0438