Diverse and dynamic roles of F-box proteins in plant biology

The SCF complex is a widely studied multi-subunit ring E3 ubiquitin ligase that tags targeted proteins with ubiquitin for protein degradation by the ubiquitin 26S-proteasome system (UPS). The UPS is an important system that generally keeps cellular events tightly regulated by purging misfolded or da...

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Bibliographic Details
Published in:Planta 2020-03, Vol.251 (3), p.68-68, Article 68
Main Authors: Abd-Hamid, Nur-Athirah, Ahmad-Fauzi, Muhammad-Izzat, Zainal, Zamri, Ismail, Ismanizan
Format: Article
Language:English
Subjects:
Agriculture
Biodegradation
Biomedical and Life Sciences
Ecology
Forestry
Life Sciences
Metabolites
miRNA
Plant hormones
Plant Sciences
Post-translation
Proteasome 26S
Protein families
Proteins
Purging
Regulatory proteins
Review
Secondary metabolites
Ubiquitin
Ubiquitin-protein ligase
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Summary:The SCF complex is a widely studied multi-subunit ring E3 ubiquitin ligase that tags targeted proteins with ubiquitin for protein degradation by the ubiquitin 26S-proteasome system (UPS). The UPS is an important system that generally keeps cellular events tightly regulated by purging misfolded or damaged proteins and selectively degrading important regulatory proteins. The specificity of this post-translational regulation is controlled by F-box proteins (FBPs) via selective recognition of a protein–protein interaction motif at the C-terminal domain. Hence, FBPs are pivotal proteins in determining the plant response in multiple scenarios. It is not surprising that the FBP family is one of the largest protein families in the plant kingdom. In this review, the roles of FBPs, specifically in plants, are compiled to provide insights into their involvement in secondary metabolites, plant stresses, phytohormone signalling, plant developmental processes and miRNA biogenesis.
ISSN:0032-0935
1432-2048
DOI:10.1007/s00425-020-03356-8